Fgfr2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Fgfr2
fibroblast growth factor receptor 2
MGI:95523

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0017134	fibroblast growth factor binding	ISO	J:155856
Molecular Function	GO:0017134	fibroblast growth factor binding	IBA	J:265628
Molecular Function	GO:0017134	fibroblast growth factor binding	IDA	J:46380
Molecular Function	GO:0017134	fibroblast growth factor binding	ISO	J:73065
Molecular Function	GO:0017134	fibroblast growth factor binding	ISO	J:73065
Molecular Function	GO:0005007	fibroblast growth factor receptor activity	ISO	J:155856
Molecular Function	GO:0005007	fibroblast growth factor receptor activity	IBA	J:265628
Molecular Function	GO:0005007	fibroblast growth factor receptor activity	ISO	J:73065
Molecular Function	GO:0008201	heparin binding	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:105263
Molecular Function	GO:0005515	protein binding	IPI	J:13170
Molecular Function	GO:0005515	protein binding	IPI	J:110570
Molecular Function	GO:0005515	protein binding	IPI	J:13170
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:60000
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IEA	J:72245
Cellular Component	GO:0005938	cell cortex	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0060076	excitatory synapse	IMP	J:159839
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-8851711
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-NUL-8853328
Cellular Component	GO:0005576	extracellular region	TAS	J:76640
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:92065
Cellular Component	GO:0005634	nucleus	IDA	J:99790
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IGI	J:109722
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:82767
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0007409	axonogenesis	IMP	J:127453
Biological Process	GO:0060348	bone development	IMP	J:114396
Biological Process	GO:0030282	bone mineralization	IMP	J:90391
Biological Process	GO:0060349	bone morphogenesis	IMP	J:58117
Biological Process	GO:0060667	branch elongation involved in salivary gland morphogenesis	IMP	J:119849
Biological Process	GO:0060667	branch elongation involved in salivary gland morphogenesis	IGI	J:119849
Biological Process	GO:0060670	branching involved in labyrinthine layer morphogenesis	IMP	J:46380
Biological Process	GO:0060442	branching involved in prostate gland morphogenesis	IMP	J:119935
Biological Process	GO:0060442	branching involved in prostate gland morphogenesis	IMP	J:82767
Biological Process	GO:0060442	branching involved in prostate gland morphogenesis	IMP	J:119911
Biological Process	GO:0060445	branching involved in salivary gland morphogenesis	IMP	J:74539
Biological Process	GO:0048755	branching morphogenesis of a nerve	IMP	J:127453
Biological Process	GO:0060449	bud elongation involved in lung branching	IMP	J:114396
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:137691
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:137691
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:95803
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:95803
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:95803
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:109722
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:95803
Biological Process	GO:0051301	cell division	IMP	J:85732
Biological Process	GO:0045165	cell fate commitment	IMP	J:114396
Biological Process	GO:0045165	cell fate commitment	IDA	J:94813
Biological Process	GO:0008283	cell population proliferation	IMP	J:85732
Biological Process	GO:0008283	cell population proliferation	IMP	J:90909
Biological Process	GO:0008283	cell population proliferation	IMP	J:90909
Biological Process	GO:0008283	cell population proliferation	IGI	J:136711
Biological Process	GO:0008283	cell population proliferation	IGI	J:109722
Biological Process	GO:0008283	cell population proliferation	IGI	J:136711
Biological Process	GO:0007267	cell-cell signaling	IMP	J:90909
Biological Process	GO:0007267	cell-cell signaling	IMP	J:90909
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	ISO	J:155856
Biological Process	GO:0060365	coronal suture morphogenesis	IMP	J:149465
Biological Process	GO:0048565	digestive tract development	IMP	J:92361
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	ISO	J:164563
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	IMP	J:175282
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	IMP	J:183075
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	IMP	J:124918
Biological Process	GO:0048568	embryonic organ development	IMP	J:46380
Biological Process	GO:0048562	embryonic organ morphogenesis	IMP	J:98380
Biological Process	GO:0009880	embryonic pattern specification	IMP	J:124918
Biological Process	GO:0061031	endodermal digestive tract morphogenesis	IMP	J:175282
Biological Process	GO:0048730	epidermis morphogenesis	IMP	J:85732
Biological Process	GO:0030855	epithelial cell differentiation	IMP	J:124918
Biological Process	GO:0050673	epithelial cell proliferation	IGI	J:136711
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:90909
Biological Process	GO:0050673	epithelial cell proliferation	IGI	J:119849
Biological Process	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	IGI	J:119849
Biological Process	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	IMP	J:119849
Biological Process	GO:0001837	epithelial to mesenchymal transition	ISO	J:155856
Biological Process	GO:0060441	epithelial tube branching involved in lung morphogenesis	IMP	J:202949
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IGI	J:119935
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IMP	J:46380
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:119935
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:73065
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:73065
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:95803
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IMP	J:114396
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:109722
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:119849
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0035603	fibroblast growth factor receptor signaling pathway involved in hemopoiesis	IMP	J:168171
Biological Process	GO:0060595	fibroblast growth factor receptor signaling pathway involved in mammary gland specification	IMP	J:109476
Biological Process	GO:0035602	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell	IMP	J:168171
Biological Process	GO:0035607	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	IMP	J:159839
Biological Process	GO:0035604	fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow	IMP	J:168171
Biological Process	GO:0022612	gland morphogenesis	IMP	J:119935
Biological Process	GO:0031069	hair follicle morphogenesis	IMP	J:85732
Biological Process	GO:0001701	in utero embryonic development	IGI	J:123685
Biological Process	GO:0001701	in utero embryonic development	IMP	J:46380
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:72516
Biological Process	GO:0032808	lacrimal gland development	IMP	J:62162
Biological Process	GO:0060601	lateral sprouting from an epithelium	IMP	J:82767
Biological Process	GO:0070307	lens fiber cell development	IGI	J:136711
Biological Process	GO:0070307	lens fiber cell development	IMP	J:189960
Biological Process	GO:0060174	limb bud formation	IMP	J:58117
Biological Process	GO:0060174	limb bud formation	IMP	J:46380
Biological Process	GO:0048286	lung alveolus development	IMP	J:114396
Biological Process	GO:0048286	lung alveolus development	IGI	J:114396
Biological Process	GO:0030324	lung development	IMP	J:58117
Biological Process	GO:0030324	lung development	IGI	J:107406
Biological Process	GO:0030324	lung development	IGI	J:107406
Biological Process	GO:0060463	lung lobe morphogenesis	IMP	J:114396
Biological Process	GO:0060484	lung-associated mesenchyme development	IMP	J:114396
Biological Process	GO:0060484	lung-associated mesenchyme development	IGI	J:137691
Biological Process	GO:0060615	mammary gland bud formation	IMP	J:73434
Biological Process	GO:0003149	membranous septum morphogenesis	IMP	J:111148
Biological Process	GO:0048762	mesenchymal cell differentiation	IGI	J:107078
Biological Process	GO:0060915	mesenchymal cell differentiation involved in lung development	IGI	J:114396
Biological Process	GO:0010463	mesenchymal cell proliferation	IGI	J:107406
Biological Process	GO:0060916	mesenchymal cell proliferation involved in lung development	IMP	J:114396
Biological Process	GO:0030901	midbrain development	IGI	J:123685
Biological Process	GO:0140014	mitotic nuclear division	IGI	J:136711
Biological Process	GO:0140014	mitotic nuclear division	IGI	J:136711
Biological Process	GO:0140014	mitotic nuclear division	IGI	J:136711
Biological Process	GO:0016331	morphogenesis of embryonic epithelium	IMP	J:98380
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	ISO	J:155856
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IGI	J:136711
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	ISO	J:164563
Biological Process	GO:0045839	negative regulation of mitotic nuclear division	IGI	J:136711
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:114396
Biological Process	GO:0007528	neuromuscular junction development	IMP	J:126496
Biological Process	GO:0042476	odontogenesis	IMP	J:127453
Biological Process	GO:0021769	orbitofrontal cortex development	IMP	J:159839
Biological Process	GO:0035265	organ growth	IMP	J:124918
Biological Process	GO:0030916	otic vesicle formation	TAS	J:184501
Biological Process	GO:0030916	otic vesicle formation	IMP	J:46380
Biological Process	GO:0003148	outflow tract septum morphogenesis	IMP	J:111148
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IMP	J:109476
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IGI	J:137691
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IGI	J:109722
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IGI	J:95803
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IGI	J:95803
Biological Process	GO:0045787	positive regulation of cell cycle	IMP	J:159839
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:159839
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:153198
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:73065
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:153198
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IGI	J:119849
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IMP	J:90909
Biological Process	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	IMP	J:114396
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IGI	J:119935
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:183075
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IGI	J:107406
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IGI	J:107406
Biological Process	GO:0010518	positive regulation of phospholipase activity	ISO	J:164563
Biological Process	GO:1904677	positive regulation of somatic stem cell division	IMP	J:85732
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IGI	J:107406
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IMP	J:85732
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IMP	J:90909
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IGI	J:107406
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:159839
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:114396
Biological Process	GO:0050677	positive regulation of urothelial cell proliferation	IMP	J:98380
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	IMP	J:114396
Biological Process	GO:0009791	post-embryonic development	IMP	J:114396
Biological Process	GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	IMP	J:119911
Biological Process	GO:0060523	prostate epithelial cord elongation	IMP	J:119911
Biological Process	GO:0060512	prostate gland morphogenesis	IMP	J:131096
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0021860	pyramidal neuron development	IMP	J:159839
Biological Process	GO:0050678	regulation of epithelial cell proliferation	IMP	J:131096
Biological Process	GO:0050678	regulation of epithelial cell proliferation	IMP	J:119911
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	IMP	J:114396
Biological Process	GO:0060688	regulation of morphogenesis of a branching structure	IMP	J:119935
Biological Process	GO:0033688	regulation of osteoblast proliferation	IMP	J:90391
Biological Process	GO:0051150	regulation of smooth muscle cell differentiation	IMP	J:114396
Biological Process	GO:0008589	regulation of smoothened signaling pathway	IMP	J:124918
Biological Process	GO:0048608	reproductive structure development	IMP	J:82767
Biological Process	GO:0048103	somatic stem cell division	IMP	J:85732
Biological Process	GO:0060529	squamous basal epithelial stem cell differentiation involved in prostate gland acinus development	IMP	J:119911
Biological Process	GO:0048863	stem cell differentiation	IGI	J:107078
Biological Process	GO:0072089	stem cell proliferation	IGI	J:107406
Biological Process	GO:0072089	stem cell proliferation	IMP	J:85732
Biological Process	GO:0072089	stem cell proliferation	IMP	J:90909
Biological Process	GO:0048489	synaptic vesicle transport	IMP	J:126496
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628
Biological Process	GO:0001657	ureteric bud development	IGI	J:107078
Biological Process	GO:0050674	urothelial cell proliferation	IMP	J:98380
Biological Process	GO:0060979	vasculogenesis involved in coronary vascular morphogenesis	TAS	J:169941
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	IMP	J:111148
Biological Process	GO:0021847	ventricular zone neuroblast division	IMP	J:159839

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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