Aim2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Aim2
absent in melanoma 2
MGI:2686159

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140608	cysteine-type endopeptidase activator activity	ISO	J:164563
Molecular Function	GO:0140608	cysteine-type endopeptidase activator activity	ISS	J:145965
Molecular Function	GO:0140608	cysteine-type endopeptidase activator activity	ISS	J:145965
Molecular Function	GO:0140608	cysteine-type endopeptidase activator activity	ISS	J:145965
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	IDA	J:236847
Molecular Function	GO:0003690	double-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0003690	double-stranded DNA binding	IDA	J:145965
Molecular Function	GO:0003690	double-stranded DNA binding	IDA	J:205029
Molecular Function	GO:0003690	double-stranded DNA binding	IDA	J:236847
Molecular Function	GO:0003690	double-stranded DNA binding	IDA	J:293308
Molecular Function	GO:0003690	double-stranded DNA binding	IDA	J:205029
Molecular Function	GO:0003690	double-stranded DNA binding	IDA	J:145965
Molecular Function	GO:0042802	identical protein binding	IPI	J:147175
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0140677	molecular function activator activity	ISS	J:332657
Molecular Function	GO:0140677	molecular function activator activity	IDA	J:236847
Molecular Function	GO:0140677	molecular function activator activity	ISS	J:332657
Molecular Function	GO:0140677	molecular function activator activity	IDA	J:293308
Molecular Function	GO:0140677	molecular function activator activity	IDA	J:205029
Molecular Function	GO:0038187	pattern recognition receptor activity	ISO	J:164563
Molecular Function	GO:0038187	pattern recognition receptor activity	IDA	J:205029
Molecular Function	GO:0038187	pattern recognition receptor activity	IDA	J:236847
Molecular Function	GO:0038187	pattern recognition receptor activity	IDA	J:293308
Molecular Function	GO:0038187	pattern recognition receptor activity	IDA	J:205029
Molecular Function	GO:0005515	protein binding	IPI	J:332982
Molecular Function	GO:0005515	protein binding	IPI	J:145965
Molecular Function	GO:0035591	signaling adaptor activity	ISO	J:164563
Molecular Function	GO:0035591	signaling adaptor activity	ISS	J:332657
Molecular Function	GO:0035591	signaling adaptor activity	ISS	J:332657
Molecular Function	GO:0035591	signaling adaptor activity	ISS	J:332657
Molecular Function	GO:0035591	signaling adaptor activity	IDA	J:332657
Molecular Function	GO:0030546	signaling receptor activator activity	IDA	J:236847
Molecular Function	GO:0030546	signaling receptor activator activity	IDA	J:293308
Molecular Function	GO:0030546	signaling receptor activator activity	IDA	J:205029
Cellular Component	GO:0097169	AIM2 inflammasome complex	IDA	J:236847
Cellular Component	GO:0097169	AIM2 inflammasome complex	ISO	J:164563
Cellular Component	GO:0097169	AIM2 inflammasome complex	IBA	J:265628
Cellular Component	GO:0097169	AIM2 inflammasome complex	IDA	J:145965
Cellular Component	GO:0005737	cytoplasm	NAS	J:158968
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:145965
Cellular Component	GO:0005737	cytoplasm	IDA	J:145965
Cellular Component	GO:0005737	cytoplasm	IDA	J:145965
Cellular Component	GO:0005737	cytoplasm	IDA	J:205029
Cellular Component	GO:0005737	cytoplasm	IDA	J:145965
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-877385
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-877388
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-877396
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:236847
Cellular Component	GO:0035861	site of double-strand break	IDA	J:236847
Cellular Component	GO:0035861	site of double-strand break	IDA	J:236847
Cellular Component	GO:0035861	site of double-strand break	IDA	J:236847
Biological Process	GO:0002218	activation of innate immune response	IDA	J:147175
Biological Process	GO:0002218	activation of innate immune response	ISO	J:164563
Biological Process	GO:0002218	activation of innate immune response	IBA	J:265628
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	ISO	J:164563
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	IDA	J:331115
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	IDA	J:293308
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	IDA	J:254237
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	IDA	J:236847
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	IDA	J:236523
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	IDA	J:205029
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	IDA	J:236847
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	IDA	J:293308
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	IDA	J:293308
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	IDA	J:205029
Biological Process	GO:0140970	AIM2 inflammasome complex assembly	IDA	J:205029
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0007420	brain development	IDA	J:293308
Biological Process	GO:0007420	brain development	IDA	J:293308
Biological Process	GO:0035458	cellular response to interferon-beta	IBA	J:265628
Biological Process	GO:0035458	cellular response to interferon-beta	IDA	J:145965
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ISO	J:145965
Biological Process	GO:0051607	defense response to virus	NAS	J:158968
Biological Process	GO:0006974	DNA damage response	IDA	J:293308
Biological Process	GO:0006974	DNA damage response	IDA	J:236847
Biological Process	GO:0006974	DNA damage response	IDA	J:236847
Biological Process	GO:0006974	DNA damage response	IDA	J:293308
Biological Process	GO:0006974	DNA damage response	IDA	J:293308
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0032611	interleukin-1 beta production	ISO	J:145965
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IDA	J:224547
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IDA	J:228671
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IDA	J:305800
Biological Process	GO:0070050	neuron cellular homeostasis	IDA	J:293308
Biological Process	GO:0002221	pattern recognition receptor signaling pathway	NAS	J:158968
Biological Process	GO:2001056	positive regulation of cysteine-type endopeptidase activity	IMP	J:187571
Biological Process	GO:2001056	positive regulation of cysteine-type endopeptidase activity	IDA	J:147175
Biological Process	GO:2001056	positive regulation of cysteine-type endopeptidase activity	ISO	J:164563
Biological Process	GO:0002230	positive regulation of defense response to virus by host	IMP	J:146958
Biological Process	GO:0050729	positive regulation of inflammatory response	NAS	J:158968
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IDA	J:147175
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IMP	J:146958
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IDA	J:331115
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	ISO	J:164563
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IGI	J:205949
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0070269	pyroptosis	IDA	J:236847
Biological Process	GO:0070269	pyroptosis	IDA	J:293308
Biological Process	GO:0070269	pyroptosis	ISO	J:164563
Biological Process	GO:0070269	pyroptosis	IDA	J:147175
Biological Process	GO:0070269	pyroptosis	IDA	J:331115
Biological Process	GO:0070269	pyroptosis	NAS	J:158968
Biological Process	GO:0070269	pyroptosis	IDA	J:254237
Biological Process	GO:1904270	pyroptosome complex assembly	ISO	J:164563
Biological Process	GO:0050795	regulation of behavior	IDA	J:293308
Biological Process	GO:0043029	T cell homeostasis	IDA	J:305800
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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