Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables several functions, including identical protein binding activity; pattern recognition receptor activity; and signaling adaptor activity. Involved in several processes, including AIM2 inflammasome complex assembly; negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of defense response. Acts upstream of or within cellular response to interferon-beta. Part of AIM2 inflammasome complex. Is active in cytoplasm; nucleus; and site of double-strand break. Orthologous to human AIM2 (absent in melanoma 2).