GO Annotations Graph

• Symbol: Helb
• Name: helicase (DNA) B
• ID: MGI:2152895

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043139	5'-3' DNA helicase activity	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0003678	DNA helicase activity	IDA	J:72442
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0017116	single-stranded DNA helicase activity	ISO	J:164563
Molecular Function	GO:0017116	single-stranded DNA helicase activity	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:231089
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005662	DNA replication factor A complex	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:231089
Cellular Component	GO:0035861	site of double-strand break	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IMP	J:231089
Biological Process	GO:0006260	DNA replication	ISO	J:164563
Biological Process	GO:0006269	DNA replication, synthesis of RNA primer	ISO	J:164563
Biological Process	GO:0006269	DNA replication, synthesis of RNA primer	TAS	J:72442
Biological Process	GO:0006261	DNA-templated DNA replication	IDA	J:72442
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	IMP	J:231089
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:1903775	regulation of DNA double-strand break processing	IMP	J:231089
Biological Process	GO:1903775	regulation of DNA double-strand break processing	ISO	J:164563