GO Annotations Graph

• Symbol: Bbs4
• Name: Bardet-Biedl syndrome 4
• ID: MGI:2143311

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	ISO	J:164563
Molecular Function	GO:0048487	beta-tubulin binding	ISO	J:164563
Molecular Function	GO:0034452	dynactin binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:156536
Molecular Function	GO:0005515	protein binding	IPI	J:180524
Molecular Function	GO:0005515	protein binding	IPI	J:193003
Molecular Function	GO:0005515	protein binding	IPI	J:247414
Molecular Function	GO:0005515	protein binding	IPI	J:239231
Molecular Function	GO:0005515	protein binding	IPI	J:285722
Molecular Function	GO:0005515	protein binding	IPI	J:206657
Molecular Function	GO:0005515	protein binding	IPI	J:239231
Molecular Function	GO:0005515	protein binding	IPI	J:239231
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:73065
Cellular Component	GO:0034464	BBSome	IDA	J:156536
Cellular Component	GO:0034464	BBSome	IDA	J:193003
Cellular Component	GO:0034464	BBSome	ISO	J:73065
Cellular Component	GO:0034464	BBSome	IDA	J:177990
Cellular Component	GO:0034464	BBSome	IDA	J:156536
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0034451	centriolar satellite	IDA	J:239231
Cellular Component	GO:0034451	centriolar satellite	IDA	J:206657
Cellular Component	GO:0005814	centriole	ISO	J:164563
Cellular Component	GO:0005813	centrosome	IDA	J:96395
Cellular Component	GO:0005813	centrosome	ISO	J:73065
Cellular Component	GO:0036064	ciliary basal body	ISO	J:164563
Cellular Component	GO:0036064	ciliary basal body	IBA	J:265628
Cellular Component	GO:0036064	ciliary basal body	ISO	J:193954
Cellular Component	GO:0060170	ciliary membrane	ISO	J:164563
Cellular Component	GO:0035869	ciliary transition zone	ISO	J:164563
Cellular Component	GO:0005929	cilium	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0016020	membrane	IDA	J:180524
Cellular Component	GO:0031514	motile cilium	IMP	J:132765
Cellular Component	GO:0031514	motile cilium	ISO	J:164563
Cellular Component	GO:0097730	non-motile cilium	ISO	J:164563
Cellular Component	GO:0000242	pericentriolar material	ISO	J:164563
Cellular Component	GO:0032391	photoreceptor connecting cilium	IDA	J:203124
Cellular Component	GO:0001917	photoreceptor inner segment	IDA	J:139622
Cellular Component	GO:0001750	photoreceptor outer segment	IDA	J:203124
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0030534	adult behavior	IMP	J:94467
Biological Process	GO:0048854	brain morphogenesis	IMP	J:128532
Biological Process	GO:0030030	cell projection organization	IEA	J:60000
Biological Process	GO:0007098	centrosome cycle	ISO	J:164563
Biological Process	GO:0021987	cerebral cortex development	IMP	J:128532
Biological Process	GO:0060271	cilium assembly	IMP	J:132765
Biological Process	GO:0060271	cilium assembly	NAS	J:320058
Biological Process	GO:0060271	cilium assembly	IBA	J:265628
Biological Process	GO:0060271	cilium assembly	IMP	J:90812
Biological Process	GO:0060271	cilium assembly	IMP	J:90812
Biological Process	GO:0016358	dendrite development	IMP	J:92950
Biological Process	GO:0060324	face development	IMP	J:134638
Biological Process	GO:0045444	fat cell differentiation	IEP	J:135549
Biological Process	GO:0060613	fat pad development	IMP	J:134093
Biological Process	GO:0010467	gene expression	IMP	J:146158
Biological Process	GO:0010467	gene expression	IMP	J:135832
Biological Process	GO:0010467	gene expression	IMP	J:146158
Biological Process	GO:0021766	hippocampus development	IMP	J:215031
Biological Process	GO:0021766	hippocampus development	IMP	J:128532
Biological Process	GO:0033210	leptin-mediated signaling pathway	IMP	J:146158
Biological Process	GO:0051457	maintenance of protein location in nucleus	ISO	J:164563
Biological Process	GO:0034454	microtubule anchoring at centrosome	ISO	J:164563
Biological Process	GO:0000226	microtubule cytoskeleton organization	IMP	J:92950
Biological Process	GO:0000281	mitotic cytokinesis	ISO	J:164563
Biological Process	GO:0030837	negative regulation of actin filament polymerization	IMP	J:201104
Biological Process	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway	IMP	J:146158
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:146158
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:135832
Biological Process	GO:0034260	negative regulation of GTPase activity	IMP	J:201104
Biological Process	GO:0003085	negative regulation of systemic arterial blood pressure	IMP	J:135832
Biological Process	GO:0001843	neural tube closure	IMP	J:102697
Biological Process	GO:0001764	neuron migration	IGI	J:220804
Biological Process	GO:0001764	neuron migration	IMP	J:220804
Biological Process	GO:1905515	non-motile cilium assembly	IMP	J:92950
Biological Process	GO:1905515	non-motile cilium assembly	IMP	J:215031
Biological Process	GO:1905515	non-motile cilium assembly	IMP	J:102697
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:123272
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:134093
Biological Process	GO:0045494	photoreceptor cell maintenance	IGI	J:203124
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:203124
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:169200
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:171278
Biological Process	GO:0035845	photoreceptor cell outer segment organization	IMP	J:193199
Biological Process	GO:0045724	positive regulation of cilium assembly	IMP	J:90812
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:135832
Biological Process	GO:0008104	protein localization	IMP	J:181886
Biological Process	GO:0071539	protein localization to centrosome	ISO	J:164563
Biological Process	GO:0071539	protein localization to centrosome	ISO	J:155856
Biological Process	GO:0061512	protein localization to cilium	ISO	J:164563
Biological Process	GO:0061512	protein localization to cilium	IBA	J:265628
Biological Process	GO:0033365	protein localization to organelle	IDA	J:133334
Biological Process	GO:1903546	protein localization to photoreceptor outer segment	IMP	J:171278
Biological Process	GO:1903546	protein localization to photoreceptor outer segment	IMP	J:139622
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0060296	regulation of cilium beat frequency involved in ciliary motility	IMP	J:132765
Biological Process	GO:0032465	regulation of cytokinesis	ISO	J:164563
Biological Process	GO:0019216	regulation of lipid metabolic process	IMP	J:90812
Biological Process	GO:1902855	regulation of non-motile cilium assembly	IMP	J:137093
Biological Process	GO:1902855	regulation of non-motile cilium assembly	IMP	J:137093
Biological Process	GO:0051492	regulation of stress fiber assembly	IMP	J:201104
Biological Process	GO:0044321	response to leptin	IMP	J:135832
Biological Process	GO:0001895	retina homeostasis	IMP	J:92950
Biological Process	GO:0001895	retina homeostasis	IMP	J:90812
Biological Process	GO:0046548	retinal rod cell development	IMP	J:90812
Biological Process	GO:0007608	sensory perception of smell	IMP	J:92950
Biological Process	GO:0035176	social behavior	IMP	J:134093
Biological Process	GO:0007286	spermatid development	IMP	J:90812
Biological Process	GO:0021756	striatum development	IMP	J:128532
Biological Process	GO:0021591	ventricular system development	IMP	J:215031