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GO Annotations Graph
Symbol
Name
ID
Rtel1
regulator of telomere elongation helicase 1
MGI:2139369

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:00515394 iron, 4 sulfur cluster bindingIEAJ:60000
Molecular FunctionGO:0005524ATP bindingISOJ:164563
Molecular FunctionGO:0004003ATP-dependent DNA helicase activityISOJ:164563
Molecular FunctionGO:0004003ATP-dependent DNA helicase activityIDAJ:202812
Molecular FunctionGO:0008026ATP-dependent helicase activityIEAJ:72247
Molecular FunctionGO:0003677DNA bindingIEAJ:60000
Molecular FunctionGO:0003677DNA bindingIEAJ:72247
Molecular FunctionGO:0070182DNA polymerase bindingIPIJ:202812
Molecular FunctionGO:0004386helicase activityTASJ:222674
Molecular FunctionGO:0016787hydrolase activityIEAJ:60000
Molecular FunctionGO:0016818hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesIEAJ:72247
Molecular FunctionGO:0051536iron-sulfur cluster bindingIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0003676nucleic acid bindingIEAJ:72247
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:202812
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0005634nucleusIDAJ:91351
Biological ProcessGO:0006974cellular response to DNA damage stimulusIEAJ:60000
Biological ProcessGO:0032508DNA duplex unwindingIDAJ:202812
Biological ProcessGO:0006310DNA recombinationIEAJ:72247
Biological ProcessGO:0006281DNA repairIEAJ:72247
Biological ProcessGO:0006281DNA repairIEAJ:60000
Biological ProcessGO:0006260DNA replicationIEAJ:72247
Biological ProcessGO:1902990mitotic telomere maintenance via semi-conservative replicationIDAJ:202812
Biological ProcessGO:1904430negative regulation of t-circle formationIMPJ:222674
Biological ProcessGO:1904430negative regulation of t-circle formationIMPJ:202812
Biological ProcessGO:1904506negative regulation of telomere maintenance in response to DNA damageIMPJ:222674
Biological ProcessGO:0006139nucleobase-containing compound metabolic processIEAJ:72247
Biological ProcessGO:1904355positive regulation of telomere cappingISOJ:164563
Biological ProcessGO:0032206positive regulation of telomere maintenanceIMPJ:222674
Biological ProcessGO:1904358positive regulation of telomere maintenance via telomere lengtheningISOJ:164563
Biological ProcessGO:1904535positive regulation of telomeric loop disassemblyIDAJ:222674
Biological ProcessGO:0010569regulation of double-strand break repair via homologous recombinationISOJ:164563
Biological ProcessGO:0031297replication fork processingIDAJ:202812
Biological ProcessGO:0000723telomere maintenanceIMPJ:91351
Biological ProcessGO:0000723telomere maintenanceISOJ:164563
Biological ProcessGO:0043247telomere maintenance in response to DNA damageIMPJ:222674
Biological ProcessGO:0090657telomeric loop disassemblyIDAJ:222674
Biological ProcessGO:0090657telomeric loop disassemblyIMPJ:202812


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/13/2022
MGI 6.21
The Jackson Laboratory