GO Annotations Graph

• Symbol: Rpa1
• Name: replication protein A1
• ID: MGI:1915525

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:78200
Molecular Function	GO:0003684	damaged DNA binding	ISO	J:164563
Molecular Function	GO:0003684	damaged DNA binding	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0098505	G-rich strand telomeric DNA binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0043047	single-stranded telomeric DNA binding	IBA	J:265628
Cellular Component	GO:0000793	condensed chromosome	IDA	J:78200
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:161203
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:182264
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:135578
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:131722
Cellular Component	GO:0005662	DNA replication factor A complex	ISO	J:155856
Cellular Component	GO:0005662	DNA replication factor A complex	IBA	J:265628
Cellular Component	GO:0005662	DNA replication factor A complex	ISO	J:73065
Cellular Component	GO:0000800	lateral element	IDA	J:176168
Cellular Component	GO:0000800	lateral element	IDA	J:185266
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:123677
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912421
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912431
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912462
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912487
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:71817
Cellular Component	GO:0016605	PML body	ISO	J:73065
Cellular Component	GO:0090734	site of DNA damage	ISO	J:164563
Biological Process	GO:0006284	base-excision repair	ISO	J:164563
Biological Process	GO:0051276	chromosome organization	IMP	J:99303
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006310	DNA recombination	IEA	J:60000
Biological Process	GO:0006310	DNA recombination	IEA	J:72247
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0006260	DNA replication	ISO	J:164563
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IBA	J:265628
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IMP	J:93303
Biological Process	GO:0030097	hemopoiesis	IMP	J:99303
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IMP	J:99303
Biological Process	GO:0001701	in utero embryonic development	IMP	J:93303
Biological Process	GO:0051321	meiotic cell cycle	IBA	J:265628
Biological Process	GO:0051321	meiotic cell cycle	IDA	J:78200
Biological Process	GO:0006298	mismatch repair	ISO	J:164563
Biological Process	GO:0006289	nucleotide-excision repair	ISO	J:164563
Biological Process	GO:0006289	nucleotide-excision repair	IBA	J:265628
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:99303
Biological Process	GO:0034502	protein localization to chromosome	ISO	J:164563
Biological Process	GO:0000723	telomere maintenance	ISO	J:164563
Biological Process	GO:0007004	telomere maintenance via telomerase	IBA	J:265628