GO Annotations Graph

• Symbol: Fstl3
• Name: follistatin-like 3
• ID: MGI:1890391

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0048185	activin binding	ISO	J:164563
Molecular Function	GO:0048185	activin binding	IBA	J:265628
Molecular Function	GO:0048185	activin binding	IDA	J:66713
Molecular Function	GO:0001968	fibronectin binding	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:73442
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0044306	neuron projection terminus	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0030141	secretory granule	ISO	J:155856
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	IBA	J:265628
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	ISO	J:164563
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IDA	J:66713
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	ISO	J:164563
Biological Process	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	ISO	J:164563
Biological Process	GO:0001503	ossification	IEA	J:60000
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0030510	regulation of BMP signaling pathway	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563