GO Annotations Graph

• Symbol: Ikzf1
• Name: IKAROS family zinc finger 1
• ID: MGI:1342540

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:73976
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IBA	J:265628
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:21613
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:190693
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:142858
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008187	poly-pyrimidine tract binding	IDA	J:182882
Molecular Function	GO:0005515	protein binding	IPI	J:40023
Molecular Function	GO:0005515	protein binding	IPI	J:97581
Molecular Function	GO:0005515	protein binding	IPI	J:97581
Molecular Function	GO:0005515	protein binding	IPI	J:182882
Molecular Function	GO:0005515	protein binding	IPI	J:97581
Molecular Function	GO:0005515	protein binding	IPI	J:97581
Molecular Function	GO:0005515	protein binding	IPI	J:97581
Molecular Function	GO:0005515	protein binding	IPI	J:97581
Molecular Function	GO:0005515	protein binding	IPI	J:182882
Molecular Function	GO:0005515	protein binding	IPI	J:97581
Molecular Function	GO:0005515	protein binding	IPI	J:97581
Molecular Function	GO:0005515	protein binding	IPI	J:54004
Molecular Function	GO:0005515	protein binding	IPI	J:182882
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:97402
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:182882
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:182882
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:142858
Molecular Function	GO:0043565	sequence-specific DNA binding	IMP	J:20671
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:142858
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:21613
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9017129
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:182882
Cellular Component	GO:0005634	nucleus	IDA	J:21613
Cellular Component	GO:0005634	nucleus	IDA	J:106071
Cellular Component	GO:0005721	pericentric heterochromatin	ISO	J:164563
Cellular Component	GO:0005721	pericentric heterochromatin	IDA	J:97581
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:190693
Cellular Component	GO:0032993	protein-DNA complex	IDA	J:182882
Cellular Component	GO:0005667	transcription regulator complex	TAS	J:73976
Biological Process	GO:0035881	amacrine cell differentiation	IDA	J:219894
Biological Process	GO:0030183	B cell differentiation	IMP	J:190693
Biological Process	GO:0030183	B cell differentiation	IMP	J:20671
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0030218	erythrocyte differentiation	ISO	J:164563
Biological Process	GO:0045184	establishment of protein localization	IMP	J:182882
Biological Process	GO:0030900	forebrain development	IMP	J:106071
Biological Process	GO:0030900	forebrain development	IMP	J:97402
Biological Process	GO:0048732	gland development	IMP	J:106071
Biological Process	GO:0030097	hemopoiesis	IMP	J:73976
Biological Process	GO:0048535	lymph node development	IMP	J:20671
Biological Process	GO:0030098	lymphocyte differentiation	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0001779	natural killer cell differentiation	IMP	J:20671
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:142858
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:97581
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:142858
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:82406
Biological Process	GO:0048541	Peyer's patch development	IMP	J:20671
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:21613
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:182882
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IGI	J:106071
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:106071
Biological Process	GO:0045660	positive regulation of neutrophil differentiation	IMP	J:82647
Biological Process	GO:0045899	positive regulation of RNA polymerase II transcription preinitiation complex assembly	IMP	J:182882
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:106071
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:97402
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	IMP	J:182882
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:73976
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:190693
Biological Process	GO:0060040	retinal bipolar neuron differentiation	IDA	J:219894
Biological Process	GO:0030217	T cell differentiation	IMP	J:20671
Biological Process	GO:0048538	thymus development	IMP	J:20671