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GO Annotations Graph
Symbol
Name
ID
Trp73
transformation related protein 73
MGI:1336991

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003682chromatin bindingIBAJ:161428
Molecular FunctionGO:0003684damaged DNA bindingIBAJ:161428
Molecular FunctionGO:0003677DNA bindingIDAJ:104687
Molecular FunctionGO:0003690double-stranded DNA bindingIBAJ:161428
Molecular FunctionGO:0042802identical protein bindingISOJ:164563
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0002039p53 bindingIPIJ:63419
Molecular FunctionGO:0005515protein bindingIPIJ:200512
Molecular FunctionGO:0005515protein bindingIPIJ:97170
Molecular FunctionGO:0019901protein kinase bindingISOJ:164563
Molecular FunctionGO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingISOJ:164563
Molecular FunctionGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA bindingISOJ:164563
Molecular FunctionGO:0043565sequence-specific DNA bindingISOJ:155856
Molecular FunctionGO:0043565sequence-specific DNA bindingIBAJ:161428
Molecular FunctionGO:0003700transcription factor activity, sequence-specific DNA bindingIDAJ:104726
Molecular FunctionGO:0003700transcription factor activity, sequence-specific DNA bindingISOJ:105215
Molecular FunctionGO:0008134transcription factor bindingISOJ:164563
Molecular FunctionGO:0044212transcription regulatory region DNA bindingISOJ:164563
Molecular FunctionGO:0001077transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingISOJ:164563
Cellular ComponentGO:0030054cell junctionISOJ:164563
Cellular ComponentGO:0000785chromatinIBAJ:161428
Cellular ComponentGO:0000785chromatinISOJ:155856
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005829cytosolIBAJ:161428
Cellular ComponentGO:0005794Golgi apparatusISOJ:164563
Cellular ComponentGO:0043231intracellular membrane-bounded organelleISOJ:164563
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005634nucleusIDAJ:96577
Cellular ComponentGO:0005634nucleusIDAJ:86247
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0005634nucleusIDAJ:224739
Cellular ComponentGO:0005634nucleusIDAJ:97170
Cellular ComponentGO:0005667transcription factor complexIBAJ:161428
Biological ProcessGO:0000187activation of MAPK activityISOJ:155856
Biological ProcessGO:0006915apoptotic processIEAJ:72247
Biological ProcessGO:0006915apoptotic processIEAJ:60000
Biological ProcessGO:0007049cell cycleIEAJ:60000
Biological ProcessGO:0007050cell cycle arrestIDAJ:104726
Biological ProcessGO:0006974cellular response to DNA damage stimulusISOJ:164563
Biological ProcessGO:0006974cellular response to DNA damage stimulusIMPJ:104726
Biological ProcessGO:0034644cellular response to UVIBAJ:161428
Biological ProcessGO:0033326cerebrospinal fluid secretionIMPJ:60896
Biological ProcessGO:0048546digestive tract morphogenesisIMPJ:60896
Biological ProcessGO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorIBAJ:161428
Biological ProcessGO:0030900forebrain developmentIMPJ:96577
Biological ProcessGO:0021766hippocampus developmentIMPJ:60896
Biological ProcessGO:0006954inflammatory responseIMPJ:60896
Biological ProcessGO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorISOJ:164563
Biological ProcessGO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorIBAJ:161428
Biological ProcessGO:0031571mitotic G1 DNA damage checkpointIBAJ:161428
Biological ProcessGO:0060044negative regulation of cardiac muscle cell proliferationISOJ:139804
Biological ProcessGO:0008285negative regulation of cell proliferationISOJ:164563
Biological ProcessGO:0043508negative regulation of JUN kinase activityIDAJ:97170
Biological ProcessGO:0043524negative regulation of neuron apoptotic processIMPJ:97170
Biological ProcessGO:0043524negative regulation of neuron apoptotic processIDAJ:63419
Biological ProcessGO:0043524negative regulation of neuron apoptotic processIMPJ:109212
Biological ProcessGO:0043524negative regulation of neuron apoptotic processIMPJ:63419
Biological ProcessGO:0043524negative regulation of neuron apoptotic processIDAJ:109212
Biological ProcessGO:0045665negative regulation of neuron differentiationISOJ:155856
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIBAJ:161428
Biological ProcessGO:0048666neuron developmentIMPJ:109212
Biological ProcessGO:0043065positive regulation of apoptotic processISOJ:155856
Biological ProcessGO:2001235positive regulation of apoptotic signaling pathwayIGIJ:104726
Biological ProcessGO:0071158positive regulation of cell cycle arrestISOJ:164563
Biological ProcessGO:0045793positive regulation of cell sizeIMPJ:97170
Biological ProcessGO:0045793positive regulation of cell sizeIMPJ:109212
Biological ProcessGO:1902167positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorIGIJ:99862
Biological ProcessGO:0048714positive regulation of oligodendrocyte differentiationISOJ:155856
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIBAJ:161428
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:105215
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIDAJ:104726
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0009791post-embryonic developmentIMPJ:97170
Biological ProcessGO:0009791post-embryonic developmentIMPJ:60896
Biological ProcessGO:0051262protein tetramerizationIEAJ:72247
Biological ProcessGO:0010468regulation of gene expressionISOJ:139804
Biological ProcessGO:0007346regulation of mitotic cell cycleISOJ:139804
Biological ProcessGO:0043523regulation of neuron apoptotic processIGIJ:97170
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:72247
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0001836release of cytochrome c from mitochondriaIDAJ:97170
Biological ProcessGO:0010332response to gamma radiationIBAJ:161428
Biological ProcessGO:0010165response to X-rayIBAJ:161428
Biological ProcessGO:0006366transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:60000


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory