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GO Annotations Graph
Symbol
Name
ID
Blm
Bloom syndrome, RecQ like helicase
MGI:1328362

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0036310annealing helicase activityISOJ:164563
Molecular FunctionGO:0005524ATP bindingISOJ:164563
Molecular FunctionGO:0043140ATP-dependent 3'-5' DNA helicase activityIDAJ:51306
Molecular FunctionGO:0004003ATP-dependent DNA helicase activityISOJ:164563
Molecular FunctionGO:0008026ATP-dependent helicase activityISOJ:164563
Molecular FunctionGO:0016887ATPase activityISOJ:164563
Molecular FunctionGO:0000405bubble DNA bindingISOJ:164563
Molecular FunctionGO:0003824catalytic activityIEAJ:72247
Molecular FunctionGO:0003677DNA bindingIEAJ:72247
Molecular FunctionGO:0003677DNA bindingIEAJ:60000
Molecular FunctionGO:0009378four-way junction helicase activityISOJ:164563
Molecular FunctionGO:0051880G-quadruplex DNA bindingISOJ:164563
Molecular FunctionGO:0004386helicase activityISOJ:164563
Molecular FunctionGO:0016787hydrolase activityIEAJ:60000
Molecular FunctionGO:0016818hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesIEAJ:72247
Molecular FunctionGO:0003676nucleic acid bindingIEAJ:72247
Molecular FunctionGO:0000166nucleotide bindingIEAJ:72247
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0002039p53 bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:92518
Molecular FunctionGO:0003697single-stranded DNA bindingISOJ:164563
Cellular ComponentGO:0000781colocalizes_with
chromosome, telomeric region
ISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:131948
Cellular ComponentGO:0005622intracellularIEAJ:72247
Cellular ComponentGO:0000800lateral elementISOJ:164563
Cellular ComponentGO:0001673male germ cell nucleusIDAJ:123677
Cellular ComponentGO:0000228nuclear chromosomeISOJ:164563
Cellular ComponentGO:0016363nuclear matrixISOJ:164563
Cellular ComponentGO:0005730nucleolusISOJ:164563
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0016605colocalizes_with
PML body
ISOJ:164563
Cellular ComponentGO:0016605PML bodyISOJ:164563
Cellular ComponentGO:0045120pronucleusIDAJ:131948
Cellular ComponentGO:0005657replication forkIDAJ:92518
Biological ProcessGO:0046632alpha-beta T cell differentiationIMPJ:118992
Biological ProcessGO:0044237cellular metabolic processIEAJ:72247
Biological ProcessGO:0072757cellular response to camptothecinISOJ:164563
Biological ProcessGO:0006974cellular response to DNA damage stimulusISOJ:164563
Biological ProcessGO:0072711cellular response to hydroxyureaISOJ:164563
Biological ProcessGO:0071479cellular response to ionizing radiationISOJ:164563
Biological ProcessGO:0051276chromosome organizationIMPJ:50843
Biological ProcessGO:0051276chromosome organizationIMPJ:93771
Biological ProcessGO:0000729DNA double-strand break processingISOJ:164563
Biological ProcessGO:0032508DNA duplex unwindingISOJ:164563
Biological ProcessGO:0006310DNA recombinationIEAJ:72247
Biological ProcessGO:0006281DNA repairIDAJ:92518
Biological ProcessGO:0006260DNA replicationIEAJ:60000
Biological ProcessGO:0006260DNA replicationIEAJ:72247
Biological ProcessGO:0000733DNA strand renaturationISOJ:164563
Biological ProcessGO:0007095mitotic G2 DNA damage checkpointISOJ:164563
Biological ProcessGO:0051782negative regulation of cell divisionISOJ:164563
Biological ProcessGO:0045910negative regulation of DNA recombinationISOJ:164563
Biological ProcessGO:0045950negative regulation of mitotic recombinationIMPJ:50843
Biological ProcessGO:0045950negative regulation of mitotic recombinationIMPJ:112115
Biological ProcessGO:0045950negative regulation of mitotic recombinationIMPJ:118992
Biological ProcessGO:0045950negative regulation of mitotic recombinationIMPJ:66261
Biological ProcessGO:0070244negative regulation of thymocyte apoptotic processIMPJ:118922
Biological ProcessGO:0070244negative regulation of thymocyte apoptotic processIGIJ:118922
Biological ProcessGO:0046641positive regulation of alpha-beta T cell proliferationIMPJ:118992
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0051259protein oligomerizationISOJ:164563
Biological ProcessGO:0051098regulation of bindingIDAJ:92518
Biological ProcessGO:0000079regulation of cyclin-dependent protein serine/threonine kinase activityISOJ:164563
Biological ProcessGO:0031297replication fork processingISOJ:164563
Biological ProcessGO:0010165response to X-rayISOJ:164563
Biological ProcessGO:0000723telomere maintenanceIGIJ:93016


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/13/2022
MGI 6.21
The Jackson Laboratory