GO Annotations Graph

• Symbol: Ulk1
• Name: unc-51 like kinase 1
• ID: MGI:1270126

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0051020	GTPase binding	ISO	J:164563
Molecular Function	GO:0051879	Hsp90 protein binding	IPI	J:215871
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:136659
Molecular Function	GO:0005515	protein binding	IPI	J:245269
Molecular Function	GO:0005515	protein binding	IPI	J:219042
Molecular Function	GO:0005515	protein binding	IPI	J:149848
Molecular Function	GO:0005515	protein binding	IPI	J:215871
Molecular Function	GO:0005515	protein binding	IPI	J:227363
Molecular Function	GO:0005515	protein binding	IPI	J:213953
Molecular Function	GO:0005515	protein binding	IPI	J:89027
Molecular Function	GO:0005515	protein binding	IPI	J:89027
Molecular Function	GO:0005515	protein binding	IPI	J:120306
Molecular Function	GO:0004672	protein kinase activity	IMP	J:183987
Molecular Function	GO:0004672	protein kinase activity	IDA	J:59129
Molecular Function	GO:0004672	protein kinase activity	IDA	J:47612
Molecular Function	GO:0019901	protein kinase binding	IPI	J:175316
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IDA	J:136659
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IMP	J:215871
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:1990316	Atg1/ULK1 kinase complex	ISO	J:164563
Cellular Component	GO:1990316	Atg1/ULK1 kinase complex	IPI	J:149848
Cellular Component	GO:1990316	Atg1/ULK1 kinase complex	IDA	J:153377
Cellular Component	GO:0005776	autophagosome	IBA	J:265628
Cellular Component	GO:0005776	autophagosome	ISO	J:73065
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:59129
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	IDA	J:89027
Cellular Component	GO:0005829	cytosol	IDA	J:149848
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0097629	extrinsic component of omegasome membrane	ISO	J:164563
Cellular Component	GO:0097632	extrinsic component of phagophore assembly site membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IDA	J:89027
Cellular Component	GO:0043005	neuron projection	IDA	J:59129
Cellular Component	GO:0043005	neuron projection	IDA	J:89027
Cellular Component	GO:0043025	neuronal cell body	IDA	J:59129
Cellular Component	GO:0000407	phagophore assembly site	ISO	J:164563
Cellular Component	GO:0000407	phagophore assembly site	IDA	J:149848
Cellular Component	GO:0000407	phagophore assembly site	IDA	J:314077
Cellular Component	GO:0000407	phagophore assembly site	IBA	J:265628
Cellular Component	GO:0000407	phagophore assembly site	IDA	J:167845
Cellular Component	GO:0034045	phagophore assembly site membrane	IDA	J:136659
Cellular Component	GO:0034045	phagophore assembly site membrane	ISO	J:164563
Biological Process	GO:0000045	autophagosome assembly	ISO	J:164563
Biological Process	GO:0000045	autophagosome assembly	IMP	J:149848
Biological Process	GO:0000045	autophagosome assembly	IDA	J:314078
Biological Process	GO:0000045	autophagosome assembly	IBA	J:265628
Biological Process	GO:0006914	autophagy	ISO	J:164563
Biological Process	GO:0006914	autophagy	IMP	J:175316
Biological Process	GO:0006914	autophagy	IMP	J:136659
Biological Process	GO:0048675	axon extension	IBA	J:265628
Biological Process	GO:0048675	axon extension	IMP	J:120306
Biological Process	GO:0007409	axonogenesis	IDA	J:89027
Biological Process	GO:0034198	cellular response to amino acid starvation	IGI	J:215871
Biological Process	GO:0031669	cellular response to nutrient levels	IDA	J:175316
Biological Process	GO:0021707	cerebellar granule cell differentiation	IMP	J:59129
Biological Process	GO:0048668	collateral sprouting	IMP	J:120306
Biological Process	GO:0048668	collateral sprouting	IMP	J:120306
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:120306
Biological Process	GO:0044805	late nucleophagy	IBA	J:265628
Biological Process	GO:0016236	macroautophagy	IGI	J:215871
Biological Process	GO:0016236	macroautophagy	ISO	J:164563
Biological Process	GO:0016236	macroautophagy	IMP	J:175316
Biological Process	GO:0000423	mitophagy	IMP	J:215871
Biological Process	GO:0008285	negative regulation of cell population proliferation	IDA	J:314079
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0048671	negative regulation of collateral sprouting	IBA	J:265628
Biological Process	GO:0048671	negative regulation of collateral sprouting	IMP	J:120306
Biological Process	GO:0031333	negative regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0001764	neuron migration	IMP	J:59129
Biological Process	GO:0031175	neuron projection development	ISO	J:164563
Biological Process	GO:0031175	neuron projection development	ISO	J:155856
Biological Process	GO:0031175	neuron projection development	IMP	J:59129
Biological Process	GO:0031102	neuron projection regeneration	ISO	J:155856
Biological Process	GO:0018105	peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IDA	J:215871
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0034727	piecemeal microautophagy of the nucleus	IBA	J:265628
Biological Process	GO:2000786	positive regulation of autophagosome assembly	ISO	J:155856
Biological Process	GO:0010508	positive regulation of autophagy	IMP	J:183987
Biological Process	GO:0010508	positive regulation of autophagy	ISO	J:164563
Biological Process	GO:0010508	positive regulation of autophagy	IDA	J:314078
Biological Process	GO:0010508	positive regulation of autophagy	IBA	J:265628
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:175316
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:164563
Biological Process	GO:0046777	protein autophosphorylation	IBA	J:265628
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:47612
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:59129
Biological Process	GO:0008104	protein localization	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IDA	J:314078
Biological Process	GO:0021933	radial glia guided migration of cerebellar granule cell	IMP	J:59129
Biological Process	GO:0007265	Ras protein signal transduction	IDA	J:89027
Biological Process	GO:0031623	receptor internalization	IMP	J:120306
Biological Process	GO:0010941	regulation of cell death	IGI	J:215871
Biological Process	GO:0010468	regulation of gene expression	IGI	J:215871
Biological Process	GO:0016241	regulation of macroautophagy	ISO	J:164563
Biological Process	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway	IMP	J:120306
Biological Process	GO:1903059	regulation of protein lipidation	ISO	J:164563
Biological Process	GO:1903059	regulation of protein lipidation	IDA	J:314078
Biological Process	GO:0098780	response to mitochondrial depolarisation	IMP	J:215871
Biological Process	GO:0042594	response to starvation	IDA	J:136659
Biological Process	GO:0061709	reticulophagy	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IEA	J:72247