Dnmt3b GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Dnmt3b
DNA methyltransferase 3B
MGI:1261819

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:155856
Molecular Function	GO:0003886	DNA (cytosine-5-)-methyltransferase activity	IDA	J:108227
Molecular Function	GO:0003886	DNA (cytosine-5-)-methyltransferase activity	ISO	J:73065
Molecular Function	GO:0003886	DNA (cytosine-5-)-methyltransferase activity	IGI	J:128981
Molecular Function	GO:0003886	DNA (cytosine-5-)-methyltransferase activity	IDA	J:48528
Molecular Function	GO:0051718	DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates	IBA	J:265628
Molecular Function	GO:0051718	DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates	IDA	J:237199
Molecular Function	GO:0051719	DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates	TAS	Reactome:R-MMU-5336380
Molecular Function	GO:0003677	DNA binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	IDA	J:182982
Molecular Function	GO:0009008	DNA-methyltransferase activity	IEA	J:72247
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IDA	J:150927
Molecular Function	GO:0005515	protein binding	IPI	J:206847
Molecular Function	GO:0005515	protein binding	IPI	J:150913
Molecular Function	GO:0005515	protein binding	IPI	J:123743
Molecular Function	GO:0005515	protein binding	IPI	J:245277
Molecular Function	GO:0005515	protein binding	IPI	J:100129
Molecular Function	GO:0005515	protein binding	IPI	J:200300
Molecular Function	GO:0005515	protein binding	IPI	J:248225
Molecular Function	GO:0005515	protein binding	IPI	J:128981
Molecular Function	GO:0005515	protein binding	IPI	J:188023
Molecular Function	GO:0005515	protein binding	IPI	J:75938
Molecular Function	GO:0005515	protein binding	IPI	J:108227
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:1902494	catalytic complex	ISO	J:164563
Cellular Component	GO:0000775	chromosome, centromeric region	IDA	J:93321
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0000792	heterochromatin	IDA	J:86777
Cellular Component	GO:0000792	heterochromatin	IDA	J:108227
Cellular Component	GO:0000792	heterochromatin	IDA	J:75938
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5336380
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5336403
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-573336
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-573376
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-573383
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:108227
Cellular Component	GO:0005634	nucleus	IDA	J:154112
Biological Process	GO:0090116	C-5 methylation of cytosine	ISO	J:164563
Biological Process	GO:0090116	C-5 methylation of cytosine	IBA	J:265628
Biological Process	GO:0090116	C-5 methylation of cytosine	IDA	J:237199
Biological Process	GO:0071230	cellular response to amino acid stimulus	IDA	J:164409
Biological Process	GO:0006306	DNA methylation	IMP	J:184415
Biological Process	GO:0006306	DNA methylation	IGI	J:108227
Biological Process	GO:0006306	DNA methylation	IGI	J:261327
Biological Process	GO:0006306	DNA methylation	IGI	J:128981
Biological Process	GO:0043045	DNA methylation involved in embryo development	IEP	J:143379
Biological Process	GO:0043045	DNA methylation involved in embryo development	IGI	J:58298
Biological Process	GO:0043045	DNA methylation involved in embryo development	IGI	J:261327
Biological Process	GO:0006346	DNA methylation-dependent heterochromatin formation	IGI	J:128981
Biological Process	GO:0006346	DNA methylation-dependent heterochromatin formation	IGI	J:128981
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	IMP	J:127808
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:184415
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0045666	positive regulation of neuron differentiation	ISO	J:155856
Biological Process	GO:0031503	protein-containing complex localization	IDA	J:108227
Biological Process	GO:0010468	regulation of gene expression	IEA	J:72247
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	IMP	J:75938
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	IMP	J:75938

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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