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GO Annotations Graph
Symbol
Name
ID
Dnmt3b
DNA methyltransferase 3B
MGI:1261819

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003682chromatin bindingISOJ:155856
Molecular FunctionGO:0003886DNA (cytosine-5-)-methyltransferase activityIDAJ:108227
Molecular FunctionGO:0003886DNA (cytosine-5-)-methyltransferase activityISOJ:73065
Molecular FunctionGO:0003886DNA (cytosine-5-)-methyltransferase activityIGIJ:128981
Molecular FunctionGO:0051718DNA (cytosine-5-)-methyltransferase activity, acting on CpG substratesISOJ:155856
Molecular FunctionGO:0003677DNA bindingIDAJ:182982
Molecular FunctionGO:0003677DNA bindingISOJ:155856
Molecular FunctionGO:0009008DNA-methyltransferase activityIEAJ:72247
Molecular FunctionGO:0042826histone deacetylase bindingISOJ:155856
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0008168methyltransferase activityIDAJ:150927
Molecular FunctionGO:0005515protein bindingIPIJ:200300
Molecular FunctionGO:0005515protein bindingIPIJ:75938
Molecular FunctionGO:0005515protein bindingIPIJ:128981
Molecular FunctionGO:0005515protein bindingIPIJ:188023
Molecular FunctionGO:0005515protein bindingIPIJ:100129
Molecular FunctionGO:0005515protein bindingIPIJ:206847
Molecular FunctionGO:0005515protein bindingIPIJ:108227
Molecular FunctionGO:0005515protein bindingIPIJ:150913
Molecular FunctionGO:0003714transcription corepressor activityISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0045322unmethylated CpG bindingISOJ:155856
Cellular ComponentGO:0000775chromosome, centromeric regionIDAJ:93321
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0000792heterochromatinIDAJ:86777
Cellular ComponentGO:0043231intracellular membrane-bounded organelleISOJ:164563
Cellular ComponentGO:0005720nuclear heterochromatinIDAJ:108227
Cellular ComponentGO:0005720nuclear heterochromatinIDAJ:75938
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005634nucleusIDAJ:108227
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005634nucleusIDAJ:154112
Cellular ComponentGO:0005634nucleusISOJ:164563
Biological ProcessGO:0090116C-5 methylation of cytosineISOJ:155856
Biological ProcessGO:0071230cellular response to amino acid stimulusIDAJ:164409
Biological ProcessGO:0006306DNA methylationIGIJ:128981
Biological ProcessGO:0006306DNA methylationIGIJ:108227
Biological ProcessGO:0006306DNA methylationIMPJ:184415
Biological ProcessGO:0010424DNA methylation on cytosine within a CG sequenceISOJ:155856
Biological ProcessGO:0060821inactivation of X chromosome by DNA methylationIMPJ:204566
Biological ProcessGO:0032259methylationIEAJ:60000
Biological ProcessGO:0006346methylation-dependent chromatin silencingIGIJ:128981
Biological ProcessGO:0045814negative regulation of gene expression, epigeneticIMPJ:127808
Biological ProcessGO:0051573negative regulation of histone H3-K9 methylationISOJ:164563
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIMPJ:184415
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedISOJ:155856
Biological ProcessGO:0010628positive regulation of gene expressionISOJ:164563
Biological ProcessGO:0051571positive regulation of histone H3-K4 methylationISOJ:164563
Biological ProcessGO:0045666positive regulation of neuron differentiationISOJ:155856
Biological ProcessGO:0031503protein complex localizationIDAJ:108227
Biological ProcessGO:0010468regulation of gene expressionIEAJ:72247
Biological ProcessGO:0006349regulation of gene expression by genetic imprintingIMPJ:75938
Biological ProcessGO:0046498S-adenosylhomocysteine metabolic processISOJ:155856
Biological ProcessGO:0046499S-adenosylmethioninamine metabolic processISOJ:155856


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/10/2020
MGI 6.16
The Jackson Laboratory