GO Annotations Graph

• Symbol: Tgif1
• Name: TGFB-induced factor homeobox 1
• ID: MGI:1194497

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:105576
Molecular Function	GO:0070410	co-SMAD binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0008432	JUN kinase binding	ISO	J:73065
Molecular Function	GO:0005515	protein binding	IPI	J:105576
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:172214
Biological Process	GO:0035881	amacrine cell differentiation	IDA	J:143246
Biological Process	GO:0008283	cell population proliferation	IMP	J:117761
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:109616
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:117761
Biological Process	GO:0048144	fibroblast proliferation	IMP	J:109616
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:117761
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:0048387	negative regulation of retinoic acid receptor signaling pathway	IMP	J:105576
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:105576
Biological Process	GO:0001843	neural tube closure	IMP	J:117761
Biological Process	GO:0030182	neuron differentiation	IDA	J:143246
Biological Process	GO:0038092	nodal signaling pathway	IGI	J:157256
Biological Process	GO:1902871	positive regulation of amacrine cell differentiation	IDA	J:143246
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	IMP	J:109616
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010470	regulation of gastrulation	IGI	J:157256
Biological Process	GO:0010470	regulation of gastrulation	IGI	J:157256
Biological Process	GO:0060041	retina development in camera-type eye	IDA	J:143246