GO Annotations Graph

• Symbol: Kpna6
• Name: karyopherin subunit alpha 6
• ID: MGI:1100836

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0061608	nuclear import signal receptor activity	IBA	J:265628
Molecular Function	GO:0061608	nuclear import signal receptor activity	IDA	J:98705
Molecular Function	GO:0008139	nuclear localization sequence binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:169875
Molecular Function	GO:0005515	protein binding	IPI	J:98705
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:72247
Cellular Component	GO:0005829	cytosol	NAS	J:165431
Cellular Component	GO:0042564	NLS-dependent protein nuclear import complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	NAS	J:165431
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0075506	entry of viral genome into host nucleus through nuclear pore complex via importin	IMP	J:241220
Biological Process	GO:0075506	entry of viral genome into host nucleus through nuclear pore complex via importin	ISO	J:241220
Biological Process	GO:0060135	maternal process involved in female pregnancy	IMP	J:171441
Biological Process	GO:0060135	maternal process involved in female pregnancy	IMP	J:171441
Biological Process	GO:0030682	mitigation of host defenses by symbiont	IMP	J:241220
Biological Process	GO:0006607	NLS-bearing protein import into nucleus	IBA	J:265628
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	IMP	J:241220
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:171441
Biological Process	GO:1903902	positive regulation of viral life cycle	IMP	J:241220
Biological Process	GO:1903902	positive regulation of viral life cycle	ISO	J:241220
Biological Process	GO:0006606	protein import into nucleus	IDA	J:98705
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:171441
Biological Process	GO:0019079	viral genome replication	IMP	J:241220