GO Annotations Graph

• Symbol: Ercc6
• Name: excision repair cross-complementing rodent repair deficiency, complementation group 6
• ID: MGI:1100494

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	ISO	J:164563
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	IBA	J:265628
Molecular Function	GO:0140658	ATP-dependent chromatin remodeler activity	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0030296	protein tyrosine kinase activator activity	ISO	J:73065
Molecular Function	GO:0070063	RNA polymerase binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Cellular Component	GO:0110016	B-WICH complex	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	NAS	J:319968
Cellular Component	GO:0005730	nucleolus	ISO	J:73065
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0090734	site of DNA damage	ISO	J:164563
Cellular Component	GO:0008023	transcription elongation factor complex	ISO	J:164563
Biological Process	GO:0006284	base-excision repair	ISO	J:164563
Biological Process	GO:0006338	chromatin remodeling	NAS	J:320057
Biological Process	GO:0000077	DNA damage checkpoint signaling	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IMP	J:70351
Biological Process	GO:0006974	DNA damage response	IMP	J:105008
Biological Process	GO:0042262	DNA protection	ISO	J:155856
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0006281	DNA repair	IGI	J:125672
Biological Process	GO:0006281	DNA repair	IGI	J:122881
Biological Process	GO:0006281	DNA repair	IGI	J:125672
Biological Process	GO:0006281	DNA repair	IMP	J:63469
Biological Process	GO:0006281	DNA repair	IGI	J:125672
Biological Process	GO:0097680	double-strand break repair via classical nonhomologous end joining	ISO	J:164563
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IMP	J:65265
Biological Process	GO:0007254	JNK cascade	IMP	J:111758
Biological Process	GO:0035264	multicellular organism growth	IGI	J:181994
Biological Process	GO:0035264	multicellular organism growth	IGI	J:181994
Biological Process	GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0022008	neurogenesis	ISO	J:164563
Biological Process	GO:0030182	neuron differentiation	ISO	J:164563
Biological Process	GO:0031175	neuron projection development	ISO	J:164563
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:118275
Biological Process	GO:0002230	positive regulation of defense response to virus by host	ISO	J:164563
Biological Process	GO:0045739	positive regulation of DNA repair	ISO	J:164563
Biological Process	GO:0045739	positive regulation of DNA repair	ISO	J:164563
Biological Process	GO:0032786	positive regulation of DNA-templated transcription, elongation	ISO	J:164563
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0035066	positive regulation of histone acetylation	NAS	J:319968
Biological Process	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	ISO	J:164563
Biological Process	GO:0045943	positive regulation of transcription by RNA polymerase I	NAS	J:319968
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NAS	J:319696
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	ISO	J:164563
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	IGI	J:181994
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	IMP	J:181994
Biological Process	GO:0006290	pyrimidine dimer repair	IMP	J:40211
Biological Process	GO:0032784	regulation of DNA-templated transcription elongation	ISO	J:164563
Biological Process	GO:0034243	regulation of transcription elongation by RNA polymerase II	ISO	J:155856
Biological Process	GO:0010332	response to gamma radiation	IMP	J:92778
Biological Process	GO:0006979	response to oxidative stress	IMP	J:81189
Biological Process	GO:0006979	response to oxidative stress	ISO	J:73065
Biological Process	GO:0000303	response to superoxide	IMP	J:92778
Biological Process	GO:0009636	response to toxic substance	IMP	J:70351
Biological Process	GO:0009411	response to UV	IMP	J:92778
Biological Process	GO:0009411	response to UV	IMP	J:112137
Biological Process	GO:0010224	response to UV-B	IMP	J:62605
Biological Process	GO:0010224	response to UV-B	IMP	J:118275
Biological Process	GO:0010165	response to X-ray	IMP	J:105008
Biological Process	GO:0010165	response to X-ray	IMP	J:118275
Biological Process	GO:0000012	single strand break repair	ISO	J:164563
Biological Process	GO:0006362	transcription elongation by RNA polymerase I	IMP	J:198536
Biological Process	GO:0006283	transcription-coupled nucleotide-excision repair	ISO	J:164563
Biological Process	GO:0006283	transcription-coupled nucleotide-excision repair	ISO	J:155856
Biological Process	GO:0006283	transcription-coupled nucleotide-excision repair	IBA	J:265628
Biological Process	GO:0006283	transcription-coupled nucleotide-excision repair	IMP	J:40211
Biological Process	GO:0006283	transcription-coupled nucleotide-excision repair	IMP	J:81189