GO Annotations Graph

• Symbol: Kpnb1
• Name: karyopherin (importin) beta 1
• ID: MGI:107532

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Wed Mar 2 12:11:24 2016.

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0051879	Hsp90 protein binding	IDA	J:152609
Molecular Function	GO:0019894	kinesin binding	ISO	J:155856
Molecular Function	GO:0008139	nuclear localization sequence binding	IBA	J:161428
Molecular Function	GO:0044822	poly(A) RNA binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:124791
Molecular Function	GO:0005515	protein binding	IPI	J:124791
Molecular Function	GO:0005515	protein binding	IPI	J:152609
Molecular Function	GO:0005515	protein binding	IPI	J:152609
Molecular Function	GO:0005515	protein binding	IPI	J:96792
Molecular Function	GO:0005515	protein binding	IPI	J:222250
Molecular Function	GO:0005515	protein binding	IPI	J:74290
Molecular Function	GO:0005515	protein binding	IPI	J:63241
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0032403	protein complex binding	ISO	J:155856
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0008565	protein transporter activity	IDA	J:98705
Molecular Function	GO:0008565	protein transporter activity	IDA	J:74290
Molecular Function	GO:0008536	Ran GTPase binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:161428
Cellular Component	GO:0071782	endoplasmic reticulum tubular network	ISO	J:164563
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005635	nuclear envelope	ISO	J:164563
Cellular Component	GO:0031965	nuclear membrane	IBA	J:161428
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0034399	nuclear periphery	IBA	J:161428
Cellular Component	GO:0005643	nuclear pore	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0043234	protein complex	IDA	J:154112
Biological Process	GO:0030953	astral microtubule organization	ISO	J:164563
Biological Process	GO:0040001	establishment of mitotic spindle localization	ISO	J:164563
Biological Process	GO:0045184	establishment of protein localization	ISO	J:164563
Biological Process	GO:0006886	intracellular protein transport	IEA	J:72247
Biological Process	GO:0007079	mitotic chromosome movement towards spindle pole	ISO	J:164563
Biological Process	GO:0007080	mitotic metaphase plate congression	ISO	J:164563
Biological Process	GO:0090307	mitotic spindle assembly	ISO	J:164563
Biological Process	GO:0006607	NLS-bearing protein import into nucleus	IBA	J:161428
Biological Process	GO:0006606	protein import into nucleus	ISO	J:99172
Biological Process	GO:0006606	protein import into nucleus	IDA	J:98705
Biological Process	GO:0000059	protein import into nucleus, docking	IBA	J:161428
Biological Process	GO:0000060	protein import into nucleus, translocation	IBA	J:161428
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0031291	Ran protein signal transduction	ISO	J:164563
Biological Process	GO:0006610	ribosomal protein import into nucleus	IDA	J:74290
Biological Process	GO:0006610	ribosomal protein import into nucleus	ISO	J:164563
Biological Process	GO:0006810	transport	IEA	J:60000

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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