Crkl GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Crkl
v-crk avian sarcoma virus CT10 oncogene homolog-like
MGI:104686

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0001784	phosphotyrosine residue binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:84101
Molecular Function	GO:0005515	protein binding	IPI	J:90089
Molecular Function	GO:0005515	protein binding	IPI	J:84101
Molecular Function	GO:0005515	protein binding	IPI	J:105263
Molecular Function	GO:0005515	protein binding	IPI	J:235913
Molecular Function	GO:0005515	protein binding	IPI	J:105263
Molecular Function	GO:0005515	protein binding	IPI	J:115703
Molecular Function	GO:0005515	protein binding	IPI	J:149152
Molecular Function	GO:0005515	protein binding	IPI	J:235913
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:260356
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9027266
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9029146
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9029147
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9029152
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9029162
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9030346
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9030353
Cellular Component	GO:0098890	extrinsic component of postsynaptic membrane	IDA	J:165470
Cellular Component	GO:0098890	extrinsic component of postsynaptic membrane	IDA	J:165470
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:165470
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:165470
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:165470
Cellular Component	GO:0031594	neuromuscular junction	IMP	J:165470
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	IDA	J:235913
Cellular Component	GO:0045202	synapse	IDA	J:235913
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	IGI	J:235913
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	IGI	J:235913
Biological Process	GO:0090630	activation of GTPase activity	IGI	J:220382
Biological Process	GO:0090630	activation of GTPase activity	IGI	J:220382
Biological Process	GO:0090630	activation of GTPase activity	IGI	J:220382
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:67826
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:105259
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:105259
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:105259
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:105259
Biological Process	GO:0001783	B cell apoptotic process	IMP	J:260356
Biological Process	GO:0001568	blood vessel development	IGI	J:105259
Biological Process	GO:0001568	blood vessel development	IGI	J:105259
Biological Process	GO:0001568	blood vessel development	IGI	J:105259
Biological Process	GO:0060326	cell chemotaxis	IGI	J:220382
Biological Process	GO:0098761	cellular response to interleukin-7	IDA	J:260356
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	ISO	J:164563
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	IDA	J:260356
Biological Process	GO:0098749	cerebellar neuron development	IGI	J:143049
Biological Process	GO:0021987	cerebral cortex development	IGI	J:143049
Biological Process	GO:1904888	cranial skeletal system development	IMP	J:251775
Biological Process	GO:0016358	dendrite development	IGI	J:143049
Biological Process	GO:0086100	endothelin receptor signaling pathway	IMP	J:251775
Biological Process	GO:0030010	establishment of cell polarity	IGI	J:220382
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IMP	J:105263
Biological Process	GO:0007507	heart development	IGI	J:105259
Biological Process	GO:0035685	helper T cell diapedesis	IGI	J:220382
Biological Process	GO:0021766	hippocampus development	IGI	J:143049
Biological Process	GO:0006629	lipid metabolic process	IGI	J:260356
Biological Process	GO:0008584	male gonad development	IMP	J:242224
Biological Process	GO:0008584	male gonad development	IMP	J:242224
Biological Process	GO:0008584	male gonad development	IMP	J:242224
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0001764	neuron migration	IMP	J:132843
Biological Process	GO:0001764	neuron migration	IGI	J:143049
Biological Process	GO:0003151	outflow tract morphogenesis	IMP	J:230261
Biological Process	GO:0003151	outflow tract morphogenesis	IMP	J:230261
Biological Process	GO:0060017	parathyroid gland development	IGI	J:105259
Biological Process	GO:0007389	pattern specification process	IGI	J:105259
Biological Process	GO:0007389	pattern specification process	IGI	J:105259
Biological Process	GO:0060465	pharynx development	IMP	J:251775
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IBA	J:265628
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:105263
Biological Process	GO:1903977	positive regulation of glial cell migration	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	IDA	J:149152
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	ISO	J:164563
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:165470
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:165470
Biological Process	GO:0038026	reelin-mediated signaling pathway	IGI	J:139781
Biological Process	GO:0038026	reelin-mediated signaling pathway	IMP	J:132843
Biological Process	GO:0038026	reelin-mediated signaling pathway	IGI	J:143049
Biological Process	GO:0033628	regulation of cell adhesion mediated by integrin	IGI	J:220382
Biological Process	GO:0001558	regulation of cell growth	IDA	J:149152
Biological Process	GO:0050773	regulation of dendrite development	IGI	J:139781
Biological Process	GO:0010468	regulation of gene expression	IMP	J:105263
Biological Process	GO:0010468	regulation of gene expression	IMP	J:242224
Biological Process	GO:0010468	regulation of gene expression	IMP	J:242224
Biological Process	GO:0010468	regulation of gene expression	IMP	J:242224
Biological Process	GO:0002685	regulation of leukocyte migration	IGI	J:220382
Biological Process	GO:1904393	regulation of skeletal muscle acetylcholine-gated channel clustering	IGI	J:235913
Biological Process	GO:1904393	regulation of skeletal muscle acetylcholine-gated channel clustering	IGI	J:235913
Biological Process	GO:2000404	regulation of T cell migration	IGI	J:220382
Biological Process	GO:0071774	response to fibroblast growth factor	IMP	J:149152
Biological Process	GO:0071774	response to fibroblast growth factor	IMP	J:105263
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	IMP	J:251775
Biological Process	GO:0007338	single fertilization	IMP	J:242224
Biological Process	GO:0007338	single fertilization	IMP	J:242224
Biological Process	GO:0007338	single fertilization	IMP	J:242224
Biological Process	GO:0007283	spermatogenesis	IMP	J:242224
Biological Process	GO:0007283	spermatogenesis	IMP	J:242224
Biological Process	GO:0007283	spermatogenesis	IMP	J:242224
Biological Process	GO:0050852	T cell receptor signaling pathway	IDA	J:137330
Biological Process	GO:0048538	thymus development	IGI	J:105259
Biological Process	GO:0001655	urogenital system development	IMP	J:242224
Biological Process	GO:0001655	urogenital system development	IMP	J:242224
Biological Process	GO:0001655	urogenital system development	IMP	J:242224

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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