Hand1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Hand1
heart and neural crest derivatives expressed 1
MGI:103577

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043425	bHLH transcription factor binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:94194
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:94194
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	IPI	J:152657
Molecular Function	GO:0042802	identical protein binding	IPI	J:113904
Molecular Function	GO:0042802	identical protein binding	IDA	J:202357
Molecular Function	GO:0005515	protein binding	IPI	J:113904
Molecular Function	GO:0005515	protein binding	IPI	J:113904
Molecular Function	GO:0005515	protein binding	IPI	J:152657
Molecular Function	GO:0005515	protein binding	IPI	J:109087
Molecular Function	GO:0005515	protein binding	IPI	J:80030
Molecular Function	GO:0005515	protein binding	IPI	J:94194
Molecular Function	GO:0005515	protein binding	IPI	J:94194
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0042803	protein homodimerization activity	IPI	J:113904
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:80030
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0001221	transcription coregulator binding	IPI	J:94194
Molecular Function	GO:0008134	transcription factor binding	IPI	J:144188
Molecular Function	GO:0008134	transcription factor binding	IPI	J:22312
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	IDA	J:152657
Cellular Component	GO:0005654	nucleoplasm	IDA	J:152657
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:94194
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:144188
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	IMP	J:89474
Biological Process	GO:0003218	cardiac left ventricle formation	ISO	J:164563
Biological Process	GO:0003219	cardiac right ventricle formation	ISO	J:164563
Biological Process	GO:0060411	cardiac septum morphogenesis	ISO	J:164563
Biological Process	GO:0060536	cartilage morphogenesis	IGI	J:128020
Biological Process	GO:0030154	cell differentiation	IGI	J:109087
Biological Process	GO:0001709	cell fate determination	NAS	J:152657
Biological Process	GO:0061371	determination of heart left/right asymmetry	IMP	J:65683
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:46383
Biological Process	GO:0003144	embryonic heart tube formation	IMP	J:65683
Biological Process	GO:0007507	heart development	IBA	J:265628
Biological Process	GO:0007507	heart development	IMP	J:46384
Biological Process	GO:0007507	heart development	IMP	J:94514
Biological Process	GO:0007507	heart development	IMP	J:94514
Biological Process	GO:0007507	heart development	IGI	J:94514
Biological Process	GO:0001947	heart looping	IMP	J:46383
Biological Process	GO:0003007	heart morphogenesis	TAS	J:94194
Biological Process	GO:0003007	heart morphogenesis	NAS	J:152657
Biological Process	GO:0001701	in utero embryonic development	IMP	J:46383
Biological Process	GO:0060485	mesenchyme development	IGI	J:128020
Biological Process	GO:0001707	mesoderm formation	IMP	J:46384
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	IDA	J:144188
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:109087
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IGI	J:128020
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:109087
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:94194
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0060707	trophoblast giant cell differentiation	IMP	J:152657
Biological Process	GO:0060707	trophoblast giant cell differentiation	IMP	J:109087
Biological Process	GO:0060707	trophoblast giant cell differentiation	IDA	J:202357
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	ISO	J:164563
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	IMP	J:46383

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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