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Fam193b Gene Detail
Summary
  • Symbol
    Fam193b
  • Name
    family with sequence similarity 193, member B
  • Synonyms
    IRIZIO, MGC:29235, MGC:38018, MGC:39032
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385851
    NCBI Gene: 212483
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:55687129-55718920 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 30.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    541 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385851
 protein coding gene Chr13:55687129-55718933 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020603
 protein coding gene Chr13:55028846-55060645 (-)
A/J MGP_AJ_G0020557
 protein coding gene Chr13:52994080-53025883 (-)
AKR/J MGP_AKRJ_G0020535
 protein coding gene Chr13:54561339-54593132 (-)
BALB/cJ MGP_BALBcJ_G0020553
 protein coding gene Chr13:53226340-53258148 (-)
C3H/HeJ MGP_C3HHeJ_G0020352
 protein coding gene Chr13:54371155-54402941 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020987
 protein coding gene Chr13:56687493-56721138 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018569
 protein coding gene Chr13:50932438-50964611 (-)
CAST/EiJ MGP_CASTEiJ_G0019866
 protein coding gene Chr13:54474544-54506384 (-)
CBA/J MGP_CBAJ_G0020312
 protein coding gene Chr13:58864016-58896164 (-)
DBA/2J MGP_DBA2J_G0020435
 protein coding gene Chr13:52545268-52577057 (-)
FVB/NJ MGP_FVBNJ_G0020414
 protein coding gene Chr13:52016789-52048583 (-)
LP/J MGP_LPJ_G0020511
 protein coding gene Chr13:55281504-55313313 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020443
 protein coding gene Chr13:58328333-58360125 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021030
 protein coding gene Chr13:54139940-54171727 (-)
PWK/PhJ MGP_PWKPhJ_G0019622
 protein coding gene Chr13:52573110-52605030 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019449
 protein coding gene Chr13:53069323-53101186 (-)
WSB/EiJ MGP_WSBEiJ_G0019928
 protein coding gene Chr13:54500202-54532010 (-)



Homology
more
  • Human Ortholog
    FAM193B, family with sequence similarity 193 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM193B, family with sequence similarity 193 member B
  • Synonyms
    IRIZIO
  • Links
    NCBI Gene ID: 54540
    neXtProt AC: NX_Q96PV7
    UniProt: Q96PV7

  • Chr Location
    5q35.3; chr5:177519788-177554586 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    749
  • Tissues
    29
  • cDNA Data
    100
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 212483 NCBI Gene Model | MGI Sequence Detail 31792 C57BL/6J ±  kb
transcript NM_001408655 RefSeq | MGI Sequence Detail 4632 C57BL/6  
polypeptide Q3U2K0 UniProt | EBI | MGI Sequence Detail 892 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 100
    cDNA 100

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:233532 Scekic-Zahirovic J, et al., Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss. EMBO J. 2016 May 17;35(10):1077-97
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory