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Hnrnpk
Gene Detail
Symbol

Name
ID
Hnrnpk
heterogeneous nuclear ribonucleoprotein K
MGI:99894
Synonyms
hnRNPK, Hnrpk, KBBP
Feature Type
protein coding gene
Genetic Map
Chromosome 13
31.04 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:58391142-58403343 bp, - strand
From VEGA annotation of GRCm38

  12202 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:81909  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Hnrnpk

Human
homologs
Human Homolog HNRNPK, heterogeneous nuclear ribonucleoprotein K
NCBI Gene ID 3190
neXtProt AC  NX_P61978
Human Synonyms  CSBP, HNRPK, TUNP
Human Chr (Location)  9q21.32-q21.33; chr9:83968083-83980660 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(36) : Gene trapped(35) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Hnrnpk interacts with 249 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (32 annotations)
Process mRNA processing, negative regulation of mRNA splicing, via spliceosome, ...
Component catalytic step 2 spliceosome, cell junction, ...
Function DNA binding, nucleic acid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (43)    Tissues (35)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 20
Northern blot 21
RT-PCR 2
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(25) cDNA(23) Primer pair(1) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000035894 (Evidence)
Ensembl Gene ModelENSMUSG00000021546 (Evidence)
Entrez Gene15387 (Evidence)
DFCITC1573657, TC1580587, TC1583106, TC1648335
NIA Mouse Gene IndexU034849, U060331, U086627, U096168, U106130, U117368
Consensus CDS ProjectCCDS49283.1
International Mouse Knockout Project StatusHnrnpk
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035894 VEGA Gene Model | MGI Sequence Detail 12202 C57BL/6J ±  kb
transcript OTTMUST00000092042 VEGA | MGI Sequence Detail 2970 Not Applicable 
polypeptide OTTMUSP00000050778 VEGA | MGI Sequence Detail 464 Not Applicable 

For the selected sequences
All sequences(174) RefSeq(18) UniProt(33)
Polymorphisms
SNPs within 2kb(22 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004087 K Homology domain
InterPro IPR009019 K homology domain, prokaryotic type
InterPro IPR004088 K Homology domain, type 1
InterPro IPR012987 ROK, N-terminal
Protein Ontology PR:000008669 heterogeneous nuclear ribonucleoprotein K
References
(Earliest) J:18981 Ostrowski J, et al., Purification, cloning, and expression of a murine phosphoprotein that binds the kappa B motif in vitro identifies it as the homolog of the human heterogeneous nuclear ribonucleoprotein K protein. Description of a novel DNA-dependent phosphorylation pocess. J Biol Chem. 1994 Jul 1;269(26):17626-34
(Latest) J:204486 Zheng S, et al., A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing. Genome Res. 2013 Jun;23(6):998-1007
All references(50)
Other
accession IDs
MGD-MRK-16689

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory