Hnrnpk
Gene Detail

Symbol

Name
ID

Hnrnpk
heterogeneous nuclear ribonucleoprotein K
MGI:99894

Synonyms

hnRNPK, Hnrpk, KBBP

Feature Type

protein coding gene

Genetic Map

Chromosome 13
31.04 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr13:58391142-58403343 bp, - strand From VEGA annotation of GRCm38   12202 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:81909  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Hnrnpk

Human
homologs

Human Homolog		HNRNPK, heterogeneous nuclear ribonucleoprotein K
NCBI Gene ID		3190
neXtProt AC		NX_P61978
Human Synonyms		CSBP, HNRPK, TUNP
Human Chr (Location)		9q21.32-q21.33; chr9:83968083-83980660 (-)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(36) : Gene trapped(35) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )

Interactions

Hnrnpk interacts with 249 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (33 annotations)

Process	mRNA processing, negative regulation of mRNA splicing, via spliceosome, ...
Component	catalytic step 2 spliceosome, cell junction, ...
Function	DNA binding, nucleic acid binding, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)

Data Summary: Results (43)    Tissues (35)    Images (4)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	20
Northern blot	21
RT-PCR	2

cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(25) cDNA(23) Primer pair(1) Other(1)
Microarray probesets(5)

Other database
links

VEGA Gene Model	OTTMUSG00000035894 (Evidence)
Ensembl Gene Model	ENSMUSG00000021546 (Evidence)
Entrez Gene	15387 (Evidence)
DFCI	TC1573657, TC1580587, TC1583106, TC1648335
NIA Mouse Gene Index	U034849, U060331, U086627, U096168, U106130, U117368
Consensus CDS Project	CCDS49283.1
International Mouse Knockout Project Status	Hnrnpk

Sequences

Length	Strain/Species
genomic	OTTMUSG00000035894	VEGA Gene Model | MGI Sequence Detail	12202	C57BL/6J
transcript	OTTMUST00000092042	VEGA | MGI Sequence Detail	2970	Not Applicable
polypeptide	OTTMUSP00000050778	VEGA | MGI Sequence Detail	464	Not Applicable

All sequences(158) RefSeq(18) UniProt(17)

Polymorphisms

SNPs within 2kb(22 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR004087	K Homology domain
InterPro	IPR009019	K homology domain, prokaryotic type
InterPro	IPR004088	K Homology domain, type 1
InterPro	IPR012987	ROK, N-terminal
Protein Ontology	PR:000008669	heterogeneous nuclear ribonucleoprotein K

References

(Earliest) J:18981 Ostrowski J, et al., Purification, cloning, and expression of a murine phosphoprotein that binds the kappa B motif in vitro identifies it as the homolog of the human heterogeneous nuclear ribonucleoprotein K protein. Description of a novel DNA-dependent phosphorylation pocess. J Biol Chem. 1994 Jul 1;269(26):17626-34
(Latest) J:212291 Lin N, et al., An evolutionarily conserved long noncoding RNA TUNA controls pluripotency and neural lineage commitment. Mol Cell. 2014 Mar 20;53(6):1005-19
All references(51)

Other
accession IDs

MGD-MRK-16689