Hnrnpk
Gene Detail

Symbol Name ID

Hnrnpk heterogeneous nuclear ribonucleoprotein K MGI:99894

Synonyms

hnRNPK, Hnrpk, KBBP

Feature Type

protein coding gene

Genetic Map

Chromosome 13

31.04 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr13:58391142-58403343 bp, - strand From VEGA annotation of GRCm38   12202 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:81909  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Hnrnpk

Human homologs

Human Homolog		HNRNPK, heterogeneous nuclear ribonucleoprotein K
NCBI Gene ID		3190
neXtProt AC		NX_P61978
Human Synonyms		CSBP, HNRPK, TUNP
Human Chr (Location)		9q21.32-q21.33; chr9:83968083-83980660 (-)  GRCh38

Alleles and phenotypes

All alleles(36) : Gene trapped(35) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )

Gene Ontology (GO) classifications

All GO classifications: (31 annotations)

Process	mRNA processing, positive regulation of low-density lipoprotein particle receptor biosynthetic process, ...
Component	catalytic step 2 spliceosome, cell junction, ...
Function	DNA binding, poly(A) RNA binding, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)

Data Summary: Results (43)    Tissues (34)    Images (4)
Theiler Stages: 21, 23, 28

Assay Type	Results
RNA in situ	20
Northern blot	21
RT-PCR	2

cDNA source data(1095)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(1098) cDNA(1096) Primer pair(1) Other(1)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000035894 (Evidence)
Ensembl Gene Model	ENSMUSG00000021546 (Evidence)
Entrez Gene	15387 (Evidence)
UniGene	142872
DFCI	TC1573657, TC1580587, TC1583106, TC1648335
NIA Mouse Gene Index	U034849, U060331, U086627, U096168, U106130, U117368
Consensus CDS Project	CCDS49283.1
International Mouse Knockout Project Status	Hnrnpk

Sequences

Length	Strain/Species
genomic	OTTMUSG00000035894	VEGA Gene Model | MGI Sequence Detail	12202	C57BL/6J
transcript	OTTMUST00000092042	VEGA | MGI Sequence Detail	2970	Not Applicable
polypeptide	OTTMUSP00000050778	VEGA | MGI Sequence Detail	464	Not Applicable

All sequences(144) RefSeq(16) UniProt(17)

Polymorphisms

SNPs within 2kb(22 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR004087	K Homology domain
InterPro	IPR009019	K homology domain, prokaryotic type
InterPro	IPR004088	K Homology domain, type 1
InterPro	IPR012987	ROK, N-terminal
Protein Ontology	PR:000008669	heterogeneous nuclear ribonucleoprotein K

References

(Earliest) J:18981 Ostrowski J, et al., Purification, cloning, and expression of a murine phosphoprotein that binds the kappa B motif in vitro identifies it as the homolog of the human heterogeneous nuclear ribonucleoprotein K protein. Description of a novel DNA-dependent phosphorylation pocess. J Biol Chem. 1994 Jul 1;269(26):17626-34
(Latest) J:198813 Yoon Y, et al., Anxiety-associated alternative polyadenylation of the serotonin transporter mRNA confers translational regulation by hnRNPK. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11624-9
All references(49)

Other accession IDs

MGD-MRK-16689