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Htr1f
Gene Detail
Symbol

Name
ID
Htr1f
5-hydroxytryptamine (serotonin) receptor 1F
MGI:99842
Synonyms
Htr1eb
Feature Type
protein coding gene
Genetic Map
Chromosome 16
37.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr16:64924729-65105784 bp, - strand
From Ensembl annotation of GRCm38

  181056 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37361  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: HTR1F
Protein SuperFamily: 5-hydroxytryptamine receptor 1
Gene Tree: Htr1f

Human
homologs
HTR1F, 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 3355
neXtProt AC: NX_P30939

Human Synonyms: 5-HT1F, 5-HT-1F, 5HT6, HTR1EL, MR77

Human Chr (Location): 3p12; chr3:87792767-87994856 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene display decreased temperature sensitivity and physiological abnormalities in nerve fibers.
 
Interactions
Htr1f interacts with 183 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Expression
Literature Summary: (4 records)
Data Summary: Results (280)    Tissues (97)    Images (37)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 43
In situ reporter (knock in) 61
RT-PCR 176
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(6) Primer pair(3)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000050783 (Evidence)
Entrez Gene 15557 (Evidence)
UniGene 5040
DFCI TC1589072
DoTS DT.91335485
NIA Mouse Gene Index U037178
Consensus CDS Project CCDS28267.1
International Mouse Phenotyping Consortium Status Htr1f
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050783 Ensembl Gene Model | MGI Sequence Detail 181056 C57BL/6J ±  kb
transcript ENSMUST00000063076 Ensembl | MGI Sequence Detail 2509 Not Applicable 
polypeptide ENSMUSP00000063136 Ensembl | MGI Sequence Detail 366 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(4) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(722 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000450 5-Hydroxytryptamine 1F receptor
InterPro IPR002231 5-hydroxytryptamine receptor family
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001165 5-hydroxytryptamine receptor 1F
References
(Earliest) J:2640 Amlaiky N, et al., Isolation of a mouse 5HT1E-like serotonin receptor expressed predominantly in hippocampus. J Biol Chem. 1992 Oct 5;267(28):19761-4
(Latest) J:194270 Guadiana SM, et al., Arborization of dendrites by developing neocortical neurons is dependent on primary cilia and type 3 adenylyl cyclase. J Neurosci. 2013 Feb 6;33(6):2626-38
All references(33)
Other
accession IDs
MGD-MRK-11006, MGD-MRK-16633, MGI:96280

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory