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Mug2
Gene Detail
 Symbol
Name
ID
Mug2
murinoglobulin 2
MGI:99836
Feature Type protein coding gene
Genetic Map
Chromosome 6
57.52 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:122006798-122085967 bp, + strand
From NCBI annotation of GRCm38

  79170 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:136663  Vertebrate Homology Class
2 mouse

Protein SuperFamily: alpha-2-macroglobulin
Gene Tree: Mug2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mug2 interacts with 77 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process negative regulation of peptidase activity
Component extracellular region, extracellular space
Function endopeptidase inhibitor activity, peptidase inhibitor activity, ...
External Resources: FuncBase
Expression
cDNA source data(23)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(26) Genomic(2) cDNA(23) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000030131 (Evidence)
Entrez Gene17837 (Evidence)
UniGene479223
DFCITC1587136
DoTSDT.94286875
NIA Mouse Gene IndexU007365
Consensus CDS ProjectCCDS39619.1
International Mouse Knockout Project StatusMug2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 17837 NCBI Gene Model | MGI Sequence Detail 79170 C57BL/6J ±  kb
transcript NM_008646 RefSeq | MGI Sequence Detail 4544 Not Specified 
polypeptide P28666 UniProt | EBI | MGI Sequence Detail 1451 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(10) UniProt(1)
Polymorphisms SNPs within 2kb(327 from dbSNP Build 137)    SNPs within 2kb including multiple locations(605)
Protein-related
information
ResourceIDDescription
InterPro IPR001599 Alpha-2-macroglobulin
InterPro IPR019742 Alpha-2-macroglobulin, conserved site
InterPro IPR002890 Alpha-2-macroglobulin, N-terminal
InterPro IPR011625 Alpha-2-macroglobulin, N-terminal 2
InterPro IPR019565 Alpha-2-macroglobulin, thiol-ester bond-forming
InterPro IPR009048 Alpha-macroglobulin, receptor-binding
InterPro IPR011626 A-macroglobulin complement component
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
InterPro IPR010916 TonB box, conserved site
Protein Ontology PR:000010928 murinoglobulin-2
Graphical View of Protein Domain Structure
References (Earliest) J:15557 Van Leuven F, et al., The alpha-macroglobulin family of proteinase inhibitors and the A/LRP receptor. Fifth International Workshop on Mouse Genome Mapping. 1991;:55
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(24)
Other
accession IDs
MGD-MRK-16626

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory