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Sec13 Gene Detail
Summary
  • Symbol
    Sec13
  • Name
    SEC13 homolog, nuclear pore and COPII coat complex component
  • Synonyms
    1110003H02Rik, Sec13l1, Sec13r
  • Feature Type
    protein coding gene
  • IDs
    MGI:99832
    NCBI Gene: 110379
  • Gene Overview
    MyGene.info: SEC13
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:113728052-113740681 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 52.84 cM, cytoband E3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    98 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99832
protein coding gene Chr6:113728052-113740743 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031137
protein coding gene Chr6:116274360-116287013 (-)
A/J MGP_AJ_G0031106
protein coding gene Chr6:111808255-111820936 (-)
AKR/J MGP_AKRJ_G0031037
protein coding gene Chr6:114814366-114827058 (-)
BALB/cJ MGP_BALBcJ_G0031117
protein coding gene Chr6:111753630-111766311 (-)
C3H/HeJ MGP_C3HHeJ_G0030591
protein coding gene Chr6:69469121-69482057 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031576
protein coding gene Chr6:119271689-119285489 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028740
protein coding gene Chr6:108835547-108848583 (-)
CAST/EiJ MGP_CASTEiJ_G0030224
protein coding gene Chr6:115273415-115286169 (-)
CBA/J MGP_CBAJ_G0030803
protein coding gene Chr6:123985107-124001605 (-)
DBA/2J MGP_DBA2J_G0030956
protein coding gene Chr6:110888753-110901726 (-)
FVB/NJ MGP_FVBNJ_G0030910
protein coding gene Chr6:109893182-109906174 (-)
LP/J MGP_LPJ_G0031036
protein coding gene Chr6:116297563-116310244 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030944
protein coding gene Chr6:128228024-128240791 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031603
protein coding gene Chr6:114835855-114850216 (-)
PWK/PhJ MGP_PWKPhJ_G0029940
protein coding gene Chr6:109850958-109864264 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029768
protein coding gene Chr6:113641727-113655909 (-)
WSB/EiJ MGP_WSBEiJ_G0030308
protein coding gene Chr6:115206158-115221339 (-)



Homology
more
  • Human Ortholog
    SEC13, SEC13 homolog, nuclear pore and COPII coat complex component
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SEC13, SEC13 homolog, nuclear pore and COPII coat complex component
    Orthology source: HomoloGene, HGNC
  • Synonyms
    D3S1231E, npp-20, SEC13L1, SEC13R
  • Links
    NCBI Gene ID: 6396
    neXtProt AC: NX_P55735
    UniProt: P55735

  • Chr Location
    3p25.3; chr3:10300929-10321188 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 6479
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SEC13
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 110379 NCBI Gene Model | MGI Sequence Detail 12630 C57BL/6J ±  kb
transcript NM_024206 RefSeq | MGI Sequence Detail 1301 C57BL/6  
polypeptide Q9D1M0 UniProt | EBI | MGI Sequence Detail 322 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-16619, MGI:1915067
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:19767 Swaroop A, et al., Molecular characterization of a novel human gene, SEC13R, related to the yeast secretory pathway gene SEC13, and mapping to a conserved linkage group on human chromosome 3p24-p25 and mouse chromosome 6. Hum Mol Genet. 1994 Aug;3(8):1281-6
  • Latest
    J:236793 Bruno J, et al., SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes. J Cell Biol. 2016 Jul 4;214(1):61-76

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory