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Cenpc1
Gene Detail
 Symbol
Name
ID
Cenpc1
centromere protein C1
MGI:99700
Feature Type protein coding gene
Genetic Map
Chromosome 5
43.56 cM, cytoband E2-E5
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:86012043-86065583 bp, - strand
From Ensembl annotation of GRCm38

  53541 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1371  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Cenpc1

Human
homologs
Human Homolog CENPC, centromere protein C
NCBI Gene ID 1060
neXtProt AC  NX_Q03188
Human Synonyms  CENP-C, CENPC1, hcp-4, MIF2
Human Chr (Location)  4q13.2; chr4:67472271-67545538 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(12) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in early embryonic lethality and mitotic abnormalities.
 
Interactions
Cenpc1 interacts with 96 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process cell cycle, cell division, ...
Component centromeric heterochromatin, chromosome, ...
Function centromeric DNA binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) Genomic(7) cDNA(15)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000029253 (Evidence)
Entrez Gene12617 (Evidence)
UniGene4649
DFCITC1587331
DoTSDT.55127485, DT.91386646, DT.97381077
NIA Mouse Gene IndexU026344
Consensus CDS ProjectCCDS39123.1
International Mouse Knockout Project StatusCenpc1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029253 Ensembl Gene Model | MGI Sequence Detail 53541 C57BL/6J ±  kb
transcript ENSMUST00000031170 Ensembl | MGI Sequence Detail 3173 Not Applicable 
polypeptide ENSMUSP00000031170 Ensembl | MGI Sequence Detail 906 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(8) UniProt(4)
Polymorphisms SNPs within 2kb(264 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025974 Mif2/CENP-C cupin domain
InterPro IPR011051 RmlC-like cupin domain
InterPro IPR014710 RmlC-like jelly roll fold
Protein Ontology PR:000005325 centromere protein C 1
References (Earliest) J:19411 McKay S, et al., Sequence homologies and linkage group conservation of the human and mouse Cenpc genes. Genomics. 1994 Jul 1;22(1):36-40
(Latest) J:190404 Morimoto A, et al., A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis. J Cell Biol. 2012 Jul 23;198(2):165-72
All references(35)
Other
accession IDs
MGD-MRK-16485

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory