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Mef2d
Gene Detail
Symbol

Name
ID
Mef2d
myocyte enhancer factor 2D
MGI:99533
Feature Type
protein coding gene
Genetic Map
Chromosome 3
38.78 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:88142372-88172086 bp, + strand
From VEGA annotation of GRCm38

  29715 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4327  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MEF2D
Gene Tree: Mef2d

Human
homologs
MEF2D, myocyte enhancer factor 2D
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 4209
neXtProt AC: NX_Q14814

Human Chr (Location): 1q12-q23; chr1:156463721-156500842 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(62) : Gene trapped(56) Targeted(6)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Mef2d interacts with 382 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (38 annotations)
Process apoptotic process, cell differentiation, ...
Component cytoplasm, intracellular membrane-bounded organelle, ...
Function activating transcription factor binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (23 records)
Data Summary: Results (163)    Tissues (93)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 10
RNA in situ 126
Western blot 2
RT-PCR 25
cDNA source data(23)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase mef2d ; ZFIN mef2d    NEW 
Molecular
reagents
All nucleic(31) cDNA(24) Primer pair(6) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000027132 (Evidence)
Ensembl Gene Model ENSMUSG00000001419 (Evidence)
Entrez Gene 17261 (Evidence)
Consensus CDS Project CCDS38479.1
International Mouse Phenotyping Consortium Status Mef2d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027132 VEGA Gene Model | MGI Sequence Detail 29715 C57BL/6J ±  kb
transcript OTTMUST00000067116 VEGA | MGI Sequence Detail 1791 Not Applicable 
polypeptide OTTMUSP00000033723 VEGA | MGI Sequence Detail 514 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(16) UniProt(5)
Polymorphisms
RFLP(1) : SNPs within 2kb(34 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR022102 Holliday junction regulator protein family C-terminal
InterPro IPR002100 Transcription factor, MADS-box
Protein Ontology PR:000010312 myocyte-specific enhancer factor 2D
References
(Earliest) J:16903 Martin JF, et al., A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing. Mol Cell Biol. 1994 Mar;14(3):1647-56
(Latest) J:211411 Choi J, et al., Modulation of lysine methylation in myocyte enhancer factor 2 during skeletal muscle cell differentiation. Nucleic Acids Res. 2014 Jan;42(1):224-34
All references(79)
Other
accession IDs
MGD-MRK-16311, MGI:2140078

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory