About   Help   FAQ
Mef2d
Gene Detail
Symbol

Name
ID
Mef2d
myocyte enhancer factor 2D
MGI:99533
Feature Type
protein coding gene
Genetic Map
Chromosome 3
38.78 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:88142372-88172086 bp, + strand
From VEGA annotation of GRCm38

  29715 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Mef2d
Mutations,
alleles, and
phenotypes
All mutations/alleles(62) : Gene trapped(56) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mef2d interacts with 382 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process apoptotic process, cell differentiation, ...
Component nucleus
Function DNA binding, enzyme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (23 records)
Data Summary: Results (155)    Tissues (89)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 10
RNA in situ 126
Western blot 2
RT-PCR 17
cDNA source data(21)
External Resources: Allen Institute   Expression Atlas
Molecular
reagents
All nucleic(28) cDNA(22) Primer pair(5) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000027132 (Evidence)
Ensembl Gene ModelENSMUSG00000001419 (Evidence)
Entrez Gene102639295, 17261
Consensus CDS ProjectCCDS38479.1
International Mouse Knockout Project StatusMef2d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027132 VEGA Gene Model | MGI Sequence Detail 29715 C57BL/6J ±  kb
transcript OTTMUST00000067116 VEGA | MGI Sequence Detail 1791 Not Applicable 
polypeptide OTTMUSP00000033723 VEGA | MGI Sequence Detail 514 Not Applicable 

For the selected sequences
All sequences(51) UniProt(9)
Polymorphisms
RFLP(1) : SNPs within 2kb(34 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR022102 Holliday junction regulator protein family C-terminal
InterPro IPR002100 Transcription factor, MADS-box
Protein Ontology PR:000010312 myocyte-specific enhancer factor 2D
References
(Earliest) J:16903 Martin JF, et al., A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing. Mol Cell Biol. 1994 Mar;14(3):1647-56
(Latest) J:210451 Chan SF, et al., ATM-dependent phosphorylation of MEF2D promotes neuronal survival after DNA damage. J Neurosci. 2014 Mar 26;34(13):4640-53
All references(76)
Other
accession IDs
MGD-MRK-16311, MGI:2140078

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory