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Ddx19a Gene Detail
Summary
  • Symbol
    Ddx19a
  • Name
    DEAD box helicase 19a
  • Synonyms
    DBP5, Ddx19, DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a, Eif4a-rs1
  • Feature Type
    protein coding gene
  • IDs
    MGI:99526
    NCBI Gene: 13680
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:110974996-110997800 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 57.86 cM, cytoband D3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    159 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99526
protein coding gene Chr8:110974991-110997823 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034132
protein coding gene Chr8:113681017-113703643 (-)
A/J MGP_AJ_G0034111
protein coding gene Chr8:109082122-109106730 (-)
AKR/J MGP_AKRJ_G0034038
protein coding gene Chr8:112266716-112298393 (-)
BALB/cJ MGP_BALBcJ_G0034105
protein coding gene Chr8:109259571-109283134 (-)
C3H/HeJ MGP_C3HHeJ_G0033816
protein coding gene Chr8:112995151-113018241 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034625
protein coding gene Chr8:117672490-117698043 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031567
protein coding gene Chr8:102068661-102089956 (-)
CAST/EiJ MGP_CASTEiJ_G0033143
protein coding gene Chr8:112607594-112632508 (-)
CBA/J MGP_CBAJ_G0033790
protein coding gene Chr8:121671191-121705568 (-)
DBA/2J MGP_DBA2J_G0033945
protein coding gene Chr8:108373400-108397307 (-)
FVB/NJ MGP_FVBNJ_G0033889
protein coding gene Chr8:107329244-107355625 (-)
LP/J MGP_LPJ_G0034035
protein coding gene Chr8:113867578-113897845 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033935
protein coding gene Chr8:124578866-124606282 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034644
protein coding gene Chr8:112238983-112266274 (-)
PWK/PhJ MGP_PWKPhJ_G0032846
protein coding gene Chr8:107953239-107976187 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032685
protein coding gene Chr8:110929374-110955371 (-)
WSB/EiJ MGP_WSBEiJ_G0033259
protein coding gene Chr8:112932021-112953060 (-)



Homology
more
  • Human Ortholog
    DDX19A, DEAD-box helicase 19A
  • Vertebrate Orthologs
    7
  • Human Ortholog
    DDX19A, DEAD-box helicase 19A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DDX19-DDX19L, DDX19L
  • Links
    NCBI Gene ID: 55308
    neXtProt AC: NX_Q9NUU7
    UniProt: Q9NUU7

  • Chr Location
    16q22.1; chr16:70346829-70373383 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015023 Ensembl Gene Model | MGI Sequence Detail 22805 C57BL/6J ±  kb
transcript ENSMUST00000040416 Ensembl | MGI Sequence Detail 2547 Not Applicable  
polypeptide ENSMUSP00000047898 Ensembl | MGI Sequence Detail 478 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 95
    cDNA 94
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-16303
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:17429 Gee SL, et al., Mouse erythroid cells express multiple putative RNA helicase genes exhibiting high sequence conservation from yeast to mammals. Gene. 1994 Mar 25;140(2):171-7
  • Latest
    J:219731 Rajakyla EK, et al., RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1. Nat Commun. 2015;6:5978

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/10/2020
MGI 6.16
The Jackson Laboratory