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Nrep
Gene Detail
 Symbol
Name
ID
Nrep
neuronal regeneration related protein
MGI:99444
Synonyms D0H4S114, P311, PTZ17, Sez17, SEZ17
Feature Type protein coding gene
Genetic Map
Chromosome 18
18.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr18:33437019-33464029 bp, - strand
From NCBI annotation of GRCm38

  27011 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:70874  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Nrep

Human
homologs
Human Homolog NREP, neuronal regeneration related protein
NCBI Gene ID 9315
neXtProt AC  NX_Q16612
Human Synonyms  C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17
Human Chr (Location)  5q22.1; chr5:111729303-111976931 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
 
Mice homozygous for a null allele exhibit impaired pole-walking, olfactory discrimination, social transmission of food preference, spatial learning, and contextual conditioning behavior.
 
Interactions
Nrep interacts with 349 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process regulation of neuron differentiation, regulation of transforming growth factor beta receptor signaling pathway
Component cytoplasm, nucleus
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (51)    Tissues (47)    Images (15)
Theiler Stages: 11, 13, 17, 19, 22, 23, 24, 26, 27, 28
Assay TypeResults
RNA in situ 47
RT-PCR 4
cDNA source data(444)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(446) cDNA(445) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000042834 (Evidence)
Entrez Gene27528 (Evidence)
UniGene407415
DFCITC1573921, TC1590325, TC1607217, TC1615081, TC1640616, TC1679873
DoTSDT.101268760, DT.110786637, DT.531047, DT.91341724, DT.94201321
NIA Mouse Gene IndexU038295
Consensus CDS ProjectCCDS37756.1
International Mouse Knockout Project StatusNrep
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 27528 NCBI Gene Model | MGI Sequence Detail 27011 C57BL/6J ±  kb
transcript NM_053078 RefSeq | MGI Sequence Detail 2223 C57BL/6 
polypeptide Q07475 UniProt | EBI | MGI Sequence Detail 68 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(203 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024417 Neuronal protein 3.1
Protein Ontology PR:000030950 neuronal regeneration-related protein
Graphical View of Protein Domain Structure
References (Earliest) J:16366 Studler JM, et al., An Abundant Messenger RNA of the Embryonic Brain Persists at a High Level in Cerebellum, Hippocampus and Olfactory Bulb During Adulthood. Eur J Neurosci. 1993 Jun 1;5(6):614-623
(Latest) J:204596 Badri KR, et al., Blood pressure homeostasis is maintained by a P311-TGF-beta axis. J Clin Invest. 2013 Oct 1;123(10):4502-12
All references(45)
Other
accession IDs
MGD-MRK-16210, MGI:2147210

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory