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Arf1 Gene Detail
Summary
  • Symbol
    Arf1
  • Name
    ADP-ribosylation factor 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:99431
    NCBI Gene: 11840
  • Gene Overview
    MyGene.info: ARF1
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:59211412-59228267 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 37.05 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    78 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99431
 protein coding gene Chr11:59211412-59228270 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018393
 protein coding gene Chr11:59028762-59045706 (-)
A/J MGP_AJ_G0018362
 protein coding gene Chr11:56774961-56791673 (-)
AKR/J MGP_AKRJ_G0018332
 protein coding gene Chr11:58674707-58692568 (-)
BALB/cJ MGP_BALBcJ_G0018333
 protein coding gene Chr11:57127055-57144394 (-)
C3H/HeJ MGP_C3HHeJ_G0018146
 protein coding gene Chr11:58553493-58570233 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018785
 protein coding gene Chr11:60903035-60922271 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016431
 protein coding gene Chr11:54025563-54042778 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0018120
 protein coding gene Chr11:63558387-63574810 (-)
DBA/2J MGP_DBA2J_G0018229
 protein coding gene Chr11:56446127-56463552 (-)
FVB/NJ MGP_FVBNJ_G0018220
 protein coding gene Chr11:56090683-56107533 (-)
LP/J MGP_LPJ_G0018302
 protein coding gene Chr11:59628634-59647620 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018244
 protein coding gene Chr11:64705356-64706258 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018826
 protein coding gene Chr11:58696237-58713108 (-)
PWK/PhJ MGP_PWKPhJ_G0017474
 protein coding gene Chr11:57026773-57044959 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023344
 protein coding gene Chr18:79936698-79939090 (+)
WSB/EiJ MGP_WSBEiJ_G0017754
 protein coding gene Chr11:58381482-58382435 (-)



Homology
more
  • Human Ortholog
    ARF1, ADP ribosylation factor 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ARF1, ADP ribosylation factor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PVNH8
  • Links
    NCBI Gene ID: 375
    neXtProt AC: NX_P84077
    UniProt: P84077

  • Chr Location
    1q42.13; chr1:228082660-228099212 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous embryos die in utero shortly after implantation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    58
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    659
  • Tissues
    18
  • cDNA Data
    34
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 11840 NCBI Gene Model | MGI Sequence Detail 16856 C57BL/6J ±  kb
transcript NM_001130408 RefSeq | MGI Sequence Detail 1991 C57BL/6  
polypeptide P84078 UniProt | EBI | MGI Sequence Detail 181 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 35
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-16195
References
more
  • Summaries
    All 54
    Developmental Gene Expression 4
    Gene Ontology 10
    Phenotypes 15
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:283951 Wang G, et al., Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice. Nat Commun. 2020 Jan 10;11(1):220
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/12/2021
MGI 6.16 		The Jackson Laboratory