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Adora1
Gene Detail
Symbol

Name
ID
Adora1
adenosine A1 receptor
MGI:99401
Synonyms
A1AR, A1-AR, A1R, AA1R, Ri
Feature Type
protein coding gene
Genetic Map
Chromosome 1
58.15 cM, cytoband E4
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:134199225-134235431 bp, - strand
From VEGA annotation of GRCm38

  36207 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20165  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: ADORA1
Protein SuperFamily: adenosine receptor
Gene Tree: Adora1

Human
homologs
ADORA1, adenosine A1 receptor
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 134
neXtProt AC: NX_P30542

Human Synonyms: RDC7

Human Chr (Location): 1q32.1; chr1:203127705-203167405 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(1) Targeted(6)
Incidental mutations (data from APF , CvDC )
Interactions
Adora1 interacts with 336 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (99)    Tissues (51)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 99
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase adora1    NEW 
Molecular
reagents
All nucleic(17) cDNA(15) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000049675 (Evidence)
Ensembl Gene Model ENSMUSG00000042429 (Evidence)
Entrez Gene 11539 (Evidence)
NIA Mouse Gene Index U021783
Consensus CDS Project CCDS15305.1
International Mouse Phenotyping Consortium Status Adora1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049675 VEGA Gene Model | MGI Sequence Detail 36207 C57BL/6J ±  kb
transcript OTTMUST00000126542 VEGA | MGI Sequence Detail 4968 Not Applicable 
polypeptide OTTMUSP00000068411 VEGA | MGI Sequence Detail 326 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(13) UniProt(9)
Polymorphisms
SNPs within 2kb(355 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001068 Adenosine A1 receptor
InterPro IPR001634 Adenosine receptor
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001575 adenosine receptor A1
References
(Earliest) J:17705 Marquardt DL, et al., Cloning of two adenosine receptor subtypes from mouse bone marrow-derived mast cells. J Immunol. 1994 May 1;152(9):4508-15
(Latest) J:214516 Aeffner F, et al., Activation of A1-adenosine receptors promotes leukocyte recruitment to the lung and attenuates acute lung injury in mice infected with influenza A/WSN/33 (H1N1) virus. J Virol. 2014 Sep 1;88(17):10214-27
All references(154)
Other
accession IDs
MGD-MRK-16162, MGI:2138349, MGI:2138644

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory