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Cdh11 Gene Detail
Summary
  • Symbol
    Cdh11
  • Name
    cadherin 11
  • Synonyms
    Cad11, OB-cadherin, osteoblast-cadherin
  • Feature Type
    protein coding gene
  • IDs
    MGI:99217
    NCBI Gene: 12552
  • Gene Overview
    MyGene.info: CDH11
Location & Maps
more
  • Sequence Map
    Chr8:102632995-102785111 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      152117 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 50.44 cM
  • Mapping Data
    6 experiments
Homology
more
  • Human Ortholog
    CDH11, cadherin 11
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CDH11, cadherin 11
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CAD11, CDHOB, OB, OSF-4
  • Links
    NCBI Gene ID: 1009
    neXtProt AC: NX_P55287

  • Chr Location
    16q21; chr16:64945226-65126112 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 1361
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CDH11
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    13 phenotype references
Homozygous mutant animals appear healthy and fertile.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031673 Ensembl Gene Model | MGI Sequence Detail 152117 C57BL/6J ±  kb
transcript ENSMUST00000075190 Ensembl | MGI Sequence Detail 4216 Not Applicable  
polypeptide ENSMUSP00000074681 Ensembl | MGI Sequence Detail 796 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1060 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 111
    Genomic 2
    cDNA 97
    Primer pair 7
    Other 5

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-15974
References
more
  • Summaries
    All 90
    Developmental Gene Expression 53
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:17789 Okazaki M, et al., Molecular cloning and characterization of OB-cadherin, a new member of cadherin family expressed in osteoblasts. J Biol Chem. 1994 Apr 22;269(16):12092-8
  • Latest
    J:226923 Bowen CJ, et al., Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturation. Dev Biol. 2015 Nov 1;407(1):145-57

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory