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Zfp53 Gene Detail
Summary
  • Symbol
    Zfp53
  • Name
    zinc finger protein 53
  • Synonyms
    D030067O06Rik, KRAZ1, zfas8, Zfp118, Zfp-53
  • Feature Type
    protein coding gene
  • IDs
    MGI:99200
    NCBI Gene: 24132
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:21709260-21730735 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 11.40 cM, cytoband A3.2
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    634 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99200
 protein coding gene Chr17:21709179-21742899 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023230
 protein coding gene Chr17:20228294-20247409 (+)
A/J MGP_AJ_G0023197
 protein coding gene Chr17:19486568-19505010 (+)
AKR/J MGP_AKRJ_G0023166
 protein coding gene Chr17:19512547-19533149 (+)
BALB/cJ MGP_BALBcJ_G0023195
 protein coding gene Chr17:19664715-19688454 (+)
C3H/HeJ MGP_C3HHeJ_G0022956
 protein coding gene Chr17:19895132-19915636 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023638
 protein coding gene Chr17:20899521-20920259 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021130
 protein coding gene Chr17:17013993-17033208 (+)
CAST/EiJ MGP_CASTEiJ_G0022469
 protein coding gene Chr17:19608765-19630882 (+)
CBA/J MGP_CBAJ_G0022931
 protein coding gene Chr17:21600583-21624671 (+)
DBA/2J MGP_DBA2J_G0023065
 protein coding gene Chr17:19114908-19135674 (+)
FVB/NJ MGP_FVBNJ_G0023031
 protein coding gene Chr17:18901629-18922302 (+)
LP/J MGP_LPJ_G0023142
 protein coding gene Chr17:20225713-20245411 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023051
 protein coding gene Chr17:21496923-21537571 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023678
 protein coding gene Chr17:19879745-19898531 (+)
PWK/PhJ MGP_PWKPhJ_G0022216
 protein coding gene Chr17:18003695-18022843 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022036
 protein coding gene Chr17:17961944-17986391 (+)
WSB/EiJ MGP_WSBEiJ_G0022529
 protein coding gene Chr17:19974698-20006405 (+)



Homology
more
  • Human Ortholog
    ZNF320, zinc finger protein 320
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF320, zinc finger protein 320
  • Synonyms
    ZFPL
  • Links
    NCBI Gene ID: 162967
    UniProt: A2RRD8

  • Chr Location
    19q13.41; chr19:52859491-52904320 (-)  GRCh38
  • Human Ortholog
    ZNF415, zinc finger protein 415
  • Synonyms
    Pact, ZfLp
  • Links
    NCBI Gene ID: 55786
    UniProt: Q09FC8

  • Chr Location
    19q13.42; chr19:53107879-53133077 (-)  GRCh38
  • Human Ortholog
    ZNF528, zinc finger protein 528
  • Links
    NCBI Gene ID: 84436
    UniProt: Q3MIS6

  • Chr Location
    19q13.41; chr19:52397849-52418412 (+)  GRCh38
  • Human Ortholog
    ZNF534, zinc finger protein 534
  • Synonyms
    KRBO3
  • Links
    NCBI Gene ID: 147658
    UniProt: Q76KX8

  • Chr Location
    19q13.41; chr19:52429148-52452315 (+)  GRCh38
  • Human Ortholog
    ZNF616, zinc finger protein 616
  • Links
    NCBI Gene ID: 90317
    UniProt: Q08AN1

  • Chr Location
    19q13.41; chr19:52113073-52139965 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    23 phenotype references
Homozygous disruption of this locus results in pigmentation abnormalities.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    767
  • Tissues
    40
  • cDNA Data
    13
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057409 Ensembl Gene Model | MGI Sequence Detail 21476 C57BL/6J ±  kb
transcript ENSMUST00000233158 Ensembl | MGI Sequence Detail 3065 Not Applicable  
polypeptide ENSMUSP00000156751 Ensembl | MGI Sequence Detail 652 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 3
    cDNA 13
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-15897, MGD-MRK-15952, MGI:1344343, MGI:2443960
References
more
  • Summaries
    All 46
    Developmental Gene Expression 3
    Phenotypes 23
  • Earliest
    J:84774 Dunn LC, Studies of the genetic variability in populations of wild house mice. II. Analysis of eight additional alleles at locus T. Genetics. 1957;42:299-311
  • Latest
    J:273736 Charron Y, et al., Two isoforms of the RAC-specific guanine nucleotide exchange factor TIAM2 act oppositely on transmission ratio distortion by the mouse t-haplotype. PLoS Genet. 2019 Feb;15(2):e1007964
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/16/2026
MGI 6.24 		The Jackson Laboratory