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Zfp53 Gene Detail
Summary
  • Symbol
    Zfp53
  • Name
    zinc finger protein 53
  • Synonyms
    D030067O06Rik, KRAZ1, zfas8, Zfp118, Zfp-53
  • Feature Type
    protein coding gene
  • IDs
    MGI:99200
    NCBI Gene: 24132
Location & Maps
more
  • Sequence Map
    Chr17:21491256-21509764 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      18509 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 11.40 cM, cytoband A3.2
  • Mapping Data
    5 experiments
Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Homozygous disruption of this locus results in pigmentation abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057409 Ensembl Gene Model | MGI Sequence Detail 18509 C57BL/6J ±  kb
transcript ENSMUST00000076664 Ensembl | MGI Sequence Detail 2058 Not Applicable  
polypeptide ENSMUSP00000075960 Ensembl | MGI Sequence Detail 652 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    86 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001909 Krueppel-associated box
    IPR013087 Zinc finger C2H2-type
Molecular
Reagents
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  • All nucleic 16
    Genomic 3
    cDNA 12
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-15897, MGD-MRK-15952, MGI:1344343, MGI:2443960
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:14373 Crossley PH, et al., A cluster of related zinc finger protein genes is deleted in the mouse embryonic lethal mutation tw18. Proc Natl Acad Sci U S A. 1991 Sep 15;88(18):7923-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory