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Zfp27 Gene Detail
Summary
  • Symbol
    Zfp27
  • Name
    zinc finger protein 27
  • Synonyms
    mkr-4, Zfp-27
  • Feature Type
    protein coding gene
  • IDs
    MGI:99174
    NCBI Gene: 22689
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:29592762-29605976 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 17.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    599 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99174
 protein coding gene Chr7:29592758-29605997 (-)
129S1/SvImJ ENSMUSG00200042953
 protein coding gene Chr7:19375699-19388930 (-)
A/J ENSMUSG00195043851
 protein coding gene Chr7:22049206-22061589 (-)
AKR/J ENSMUSG00220043150
 protein coding gene Chr7:22425806-22438190 (+)
BALB/cJ ENSMUSG00180053254
 protein coding gene Chr7:20108648-20121031 (-)
C3H/HeJ ENSMUSG00175035568
 protein coding gene Chr7:21150942-21164184 (-)
C57BL/6NJ ENSMUSG00215054333
 protein coding gene Chr7:19283599-19296847 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029491
 protein coding gene Chr7:29135179-29147317 (-)
CAST/EiJ ENSTCUG00005047796
 protein coding gene Chr7:21085404-21098797 (-)
CBA/J ENSMUSG00210025635
 protein coding gene Chr7:20344144-20357391 (-)
DBA/2J ENSMUSG00185042304
 protein coding gene Chr7:23439856-23452238 (-)
FVB/NJ ENSMUSG00205019054
 protein coding gene Chr7:20093115-20106361 (-)
JF1/MsJ ENSUMUG00000051881
 protein coding gene Chr7:27855226-27867620 (-)
LP/J ENSMUSG00230052160
 protein coding gene Chr7:28600192-28623253 (-)
NOD/ShiLtJ ENSMUSG00190036781
 protein coding gene Chr7:19769373-19782621 (-)
NZO/HlLtJ ENSMUSG00225022790
 protein coding gene Chr7:27443360-27466421 (-)
PWK/PhJ ENSLUMG00010037161
 protein coding gene Chr7:19813996-19825506 (-)
SPRET/EiJ ENSMSPG00010049072
 protein coding gene Chr7:19185223-19195276 (-)
WSB/EiJ ENSIUOG00005053547
 protein coding gene Chr7:14064783-14078015 (-)



Homology
more
  • Human Ortholog
    ZNF585A, zinc finger protein 585A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF585A, zinc finger protein 585A
  • Synonyms
    Zfp27
  • Links
    NCBI Gene ID: 199704
    UniProt: Q6P3V2

  • Chr Location
    19q13.12; chr19:37106734-37172741 (-)  GRCh38
  • Human Ortholog
    ZNF585B, zinc finger protein 585B
  • Synonyms
    SZFP41, Zfp27
  • Links
    NCBI Gene ID: 92285
    UniProt: Q52M93

  • Chr Location
    19q13.12; chr19:37181579-37218153 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    656
  • Tissues
    56
  • cDNA Data
    24
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22689 NCBI Gene Model | MGI Sequence Detail 13215 C57BL/6J ±  kb
transcript NM_001421814 RefSeq | MGI Sequence Detail 3815 C57BL/6  
polypeptide P10077 UniProt | EBI | MGI Sequence Detail 819 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-15871, MGD-MRK-15926
References
more
  • Summaries
    All 35
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:9478 Chowdhury K, et al., Specific and ubiquitous expression of different Zn finger protein genes in the mouse. Nucleic Acids Res. 1988 Nov 11;16(21):9995-10011
  • Latest
    J:384718 Wang Y, et al., Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease. J Cell Mol Med. 2023 Nov;27(22):3614-3627
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory