Vpreb3
Gene Detail

Symbol Name ID

Vpreb3 pre-B lymphocyte gene 3 MGI:98938

Synonyms

8HS-20, Vpreb-3

Feature Type

protein coding gene

Genetic Map

Chromosome 10

38.63 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr10:75943057-75949657 bp, + strand From VEGA annotation of GRCm38   6601 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:7598  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: immunoglobulin V region
Gene Tree: Vpreb3

Human homologs

Human Homolog		VPREB3, pre-B lymphocyte 3
NCBI Gene ID		29802
neXtProt AC		NX_Q9UKI3
Human Synonyms		8HS20, N27C7-2
Human Chr (Location)		22q11.23; chr22:24094930-24096630 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(32) : Targeted(3) Gene trapped(29)

Gene Ontology (GO) classifications

All GO classifications: (3 annotations)

Process	negative regulation of immunoglobulin secretion
Component	endoplasmic reticulum
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(22) Genomic(4) cDNA(18)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000016465 (Evidence)
Ensembl Gene Model	ENSMUSG00000000903 (Evidence)
Entrez Gene	22364 (Evidence)
UniGene	333851
DFCI	TC1586491
DoTS	DT.489592
NIA Mouse Gene Index	U011669
Consensus CDS Project	CCDS23940.1
International Mouse Knockout Project Status	Vpreb3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000016465	VEGA Gene Model | MGI Sequence Detail	6601	C57BL/6J
transcript	OTTMUST00000079013	VEGA | MGI Sequence Detail	729	Not Applicable
polypeptide	OTTMUSP00000042104	VEGA | MGI Sequence Detail	130	Not Applicable

All sequences(24) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(12 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007110	Immunoglobulin-like
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR013106	Immunoglobulin V-set
InterPro	IPR003596	Immunoglobulin V-set, subgroup
Protein Ontology	PR:000017317	pre-B lymphocyte protein 3

References

(Earliest) J:11860 Shirasawa T, et al., A novel gene product associated with mu chains in immature B cells. EMBO J. 1993 May;12(5):1827-34
(Latest) J:158418 Endoh-Yamagami S, et al., A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice. Dev Biol. 2010 Apr 1;340(1):41-53
All references(34)

Other accession IDs

MGD-MRK-15411, MGD-MRK-15414, MGI:2143638