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Vpreb3 Gene Detail
Summary
  • Symbol
    Vpreb3
  • Name
    pre-B lymphocyte gene 3
  • Synonyms
    8HS-20, Vpreb-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:98938
    NCBI Gene: 22364
  • Gene Overview
    MyGene.info: VPREB3
Location & Maps
more
  • Sequence Map
    Chr10:75943057-75949657 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6601 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    VPREB3, pre-B lymphocyte 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    VPREB3, pre-B lymphocyte 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    8HS20, N27C7-2
  • Links
    NCBI Gene ID: 29802
    neXtProt AC: NX_Q9UKI3

  • Chr Location
    22q11.23; chr22:23752743-23754443 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    33
  • Chemically induced (other)
    1
  • Gene trapped
    29
  • Targeted
    3
  • Genomic Mutations
    1 involving Vpreb3
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016465 VEGA Gene Model | MGI Sequence Detail 6601 C57BL/6J ±  kb
transcript OTTMUST00000079013 VEGA | MGI Sequence Detail 729 Not Applicable  
polypeptide OTTMUSP00000042104 VEGA | MGI Sequence Detail 130 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    37 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less
  • All nucleic 22
    Genomic 4
    cDNA 18

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-15411, MGD-MRK-15414, MGI:2143638
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:11860 Shirasawa T, et al., A novel gene product associated with mu chains in immature B cells. EMBO J. 1993 May;12(5):1827-34
  • Latest
    J:158418 Endoh-Yamagami S, et al., A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice. Dev Biol. 2010 Apr 1;340(1):41-53

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory