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Vpreb3 Gene Detail
Summary
  • Symbol
    Vpreb3
  • Name
    V-set pre-B cell surrogate light chain 3
  • Synonyms
    8HS-20, Vpreb-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:98938
    NCBI Gene: 22364
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:75778891-75785491 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 38.63 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98938
protein coding gene Chr10:75778859-75785491 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017373
protein coding gene Chr10:76145415-76151779 (+)
A/J MGP_AJ_G0017350
protein coding gene Chr10:73526600-73534127 (+)
AKR/J MGP_AKRJ_G0017311
protein coding gene Chr10:75501039-75509409 (+)
BALB/cJ MGP_BALBcJ_G0017310
protein coding gene Chr10:73724277-73730627 (+)
C3H/HeJ MGP_C3HHeJ_G0017134
protein coding gene Chr10:75549592-75556201 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017768
protein coding gene Chr10:78837939-78844289 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015458
protein coding gene Chr10:69977779-69984372 (+)
CAST/EiJ MGP_CASTEiJ_G0016705
protein coding gene Chr10:75866257-75872830 (+)
CBA/J MGP_CBAJ_G0017106
protein coding gene Chr10:81909197-81915563 (+)
DBA/2J MGP_DBA2J_G0017211
protein coding gene Chr10:72826260-72832899 (+)
FVB/NJ MGP_FVBNJ_G0017204
protein coding gene Chr10:71992882-71999432 (+)
LP/J MGP_LPJ_G0017284
protein coding gene Chr10:76646365-76652816 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017232
protein coding gene Chr10:84001968-84008839 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017807
protein coding gene Chr10:75536144-75542737 (+)
PWK/PhJ MGP_PWKPhJ_G0016488
protein coding gene Chr10:72655245-72661787 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016271
protein coding gene Chr10:74789247-74795876 (+)
WSB/EiJ MGP_WSBEiJ_G0016768
protein coding gene Chr10:75518847-75526464 (+)



Homology
more
  • Human Ortholog
    VPREB3, V-set pre-B cell surrogate light chain 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VPREB3, V-set pre-B cell surrogate light chain 3
  • Synonyms
    8HS20, N27C7-2
  • Links
    NCBI Gene ID: 29802
    neXtProt AC: NX_Q9UKI3
    UniProt: Q9UKI3

  • Chr Location
    22q11.23; chr22:23752743-23754425 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000000903 Ensembl Gene Model | MGI Sequence Detail 6601 C57BL/6J ±  kb
    transcript ENSMUST00000121151 Ensembl | MGI Sequence Detail 729 Not Applicable  
    polypeptide ENSMUSP00000113205 Ensembl | MGI Sequence Detail 130 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR007110 Immunoglobulin-like domain
      IPR036179 Immunoglobulin-like domain superfamily
      IPR013783 Immunoglobulin-like fold
      IPR013106 Immunoglobulin V-set domain
    Molecular
    Reagents
    less
    • All nucleic 23
      Genomic 4
      cDNA 19

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-15411, MGD-MRK-15414, MGI:2143638
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 13
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory