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Vim
Gene Detail
 Symbol
Name
ID
Vim
vimentin
MGI:98932
STS D2Mit149
Feature Type protein coding gene
Genetic Map
Chromosome 2
10.04 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(24)
Sequence Map
Chr2:13573927-13582826 bp, + strand
From VEGA annotation of GRCm38

  8900 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2538  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Vim

Human
homologs
Human Homolog VIM, vimentin
NCBI Gene ID 7431
neXtProt AC  NX_P08670
Human Synonyms  CTRCT30, HEL113
Human Chr (Location)  10p13; chr10:17227935-17237593 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human VIM
Alleles
and
phenotypes
All alleles(9) : Targeted(5) Gene trapped(4)
 
Homozygous null mutants exhibit impaired performance in motor coordination tests; cerebellum shows underdeveloped/abnormal Bergman glia and stunted, poorly branched Purkinje cells. Mutants are unable to survive experimental 75% reduction of kidney mass.
 
Alleles Annotated to Human Diseases(1)   
Gene Ontology
(GO)
classifications
All GO classifications: (49 annotations)
Process astrocyte development, Bergmann glial cell differentiation, ...
Component axon, cell body, ...
Function double-stranded RNA binding, glycoprotein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (181 records)
Data Summary: Results (267)    Tissues (240)    Images (52)
Theiler Stages: 1, 3, 4, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
Immunohistochemistry 46
RNA in situ 191
Northern blot 7
Western blot 6
RT-PCR 17
cDNA source data(712)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(727) Genomic(3) cDNA(716) Primer pair(5) Other(3)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000011231 (Evidence)
Ensembl Gene ModelENSMUSG00000026728 (Evidence)
Entrez Gene22352 (Evidence)
UniGene268000
DFCITC1573706, TC1614464, TC1760544
DoTSDT.110664621, DT.55184028, DT.94300691, DT.94393491, DT.97389709, DT.97395358
NIA Mouse Gene IndexU001401
Consensus CDS ProjectCCDS15696.1
International Mouse Knockout Project StatusVim
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011231 VEGA Gene Model | MGI Sequence Detail 8900 C57BL/6J ±  kb
transcript OTTMUST00000026365 VEGA | MGI Sequence Detail 2193 Not Applicable 
polypeptide OTTMUSP00000012058 VEGA | MGI Sequence Detail 466 Not Applicable 

For the selected sequences
All sequences(86) RefSeq(2) UniProt(10)
Polymorphisms RFLP(5) : SNPs within 2kb(88 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006821 Intermediate filament head, DNA-binding domain
InterPro IPR001664 Intermediate filament protein
InterPro IPR018039 Intermediate filament protein, conserved site
Protein Ontology PR:000017298 vimentin
References (Earliest) J:29340 Jackson BW, et al., Formation of cytoskeletal elements during mouse embryogenesis. Intermediate filaments of the cytokeratin type and desmosomes in preimplantation embryos. Differentiation. 1980;17(3):161-79
(Latest) J:204449 Andersson D, et al., Plasticity response in the contralesional hemisphere after subtle neurotrauma: gene expression profiling after partial deafferentation of the hippocampus. PLoS One. 2013;8(7):e70699
All references(313)
Other
accession IDs
MGD-MRK-15395

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory