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Upk1b
Gene Detail
Symbol

Name
ID
Upk1b
uroplakin 1B
MGI:98912
Synonyms
Tspan20, Upk1
Feature Type
protein coding gene
Genetic Map
Chromosome 16
26.87 cM, cytoband B5-C2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:38773184-38800203 bp, - strand
From Ensembl annotation of GRCm38

  27020 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5065  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: UPK1B
Gene Tree: Upk1b

Human
homologs
UPK1B, uroplakin 1B
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 7348
neXtProt AC: NX_O75841

Human Synonyms: TSPAN20, UPIB, UPK1

Human Chr (Location): 3q13.32; chr3:119173578-119205153 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice heterozygous for a reporter allele are viable, fertile, and physically and behaviorally normal.
 
Interactions
Upk1b interacts with 105 markers (Mir7-1, Mir23b, Mir27a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process epithelial cell differentiation
Component apical plasma membrane, extracellular exosome, ...
External Resources: FuncBase
Expression
Literature Summary: (13 records)
Data Summary: Results (280)    Tissues (149)    Images (31)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 2
RNA in situ 266
RT-PCR 12
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase upk1b    NEW 
Molecular
reagents
All nucleic(19) Genomic(1) cDNA(15) Primer pair(3)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000049436 (Evidence)
Entrez Gene 22268 (Evidence)
UniGene 130793
DFCI TC1583079
DoTS DT.97336888
NIA Mouse Gene Index U037041
Consensus CDS Project CCDS28174.1
International Mouse Phenotyping Consortium Status Upk1b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049436 Ensembl Gene Model | MGI Sequence Detail 27020 C57BL/6J ±  kb
transcript ENSMUST00000057767 Ensembl | MGI Sequence Detail 1769 Not Applicable 
polypeptide ENSMUSP00000052469 Ensembl | MGI Sequence Detail 260 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(214 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008952 Tetraspanin, EC2 domain
InterPro IPR018499 Tetraspanin/Peripherin
Protein Ontology PR:000017113 uroplakin-1b
References
(Earliest) J:15639 Ryan AM, et al., Chromosomal localization of uroplakin genes of cattle and mice. Mamm Genome. 1993 Nov;4(11):656-61
(Latest) J:214811 Weiss AC, et al., Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development. 2014 Sep;141(17):3420-30
All references(43)
Other
accession IDs
MGD-MRK-15365, MGD-MRK-15367, MGI:2146422

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory