Targeted disruption of this gene results in progressive degeneration of hypothalamic neurons accompanied by impaired hypothalamic control of energy balance and adult-onset obesity. Both genders are infertile due to a failure of germ cells to progress through meiosis I and hypogonadism.
|VEGA Gene Model||OTTMUSG00000005857 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000019505 (Evidence)|
|Entrez Gene||22187 (Evidence)|
|DoTS||DT.110526208, DT.91445621, DT.94281341, DT.94281452, DT.94307207, DT.94388092, DT.97395984, DT.97396120, DT.97396203|
|Consensus CDS Project||CCDS24826.1|
|International Mouse Phenotyping Consortium Status||Ubb|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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