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U2af1
Gene Detail
 Symbol
Name
ID
U2af1
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
MGI:98884
Synonyms 2010107D16Rik, 35kDa
Feature Type protein coding gene
Genetic Map
Chromosome 17
17.02 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:31647082-31658754 bp, - strand
From NCBI annotation of GRCm38

  11673 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14345  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: U2af1

Alleles
and
phenotypes
All alleles(85) : Gene trapped(83) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process mRNA processing, RNA splicing
Component nuclear speck, nucleus, ...
Function metal ion binding, nucleic acid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (249)    Tissues (120)    Images (30)
Theiler Stages: 13, 15, 17, 20, 21, 22, 23, 26, 28
Assay TypeResults
RNA in situ 231
RT-PCR 18
cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(21) Genomic(1) cDNA(18) Primer pair(2)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000061613 (Evidence)
Entrez Gene108121 (Evidence)
DFCITC1575121, TC1640194, TC1651948, TC1698012
DoTSDT.101128115, DT.101235198, DT.532581, DT.97375368
NIA Mouse Gene IndexU017459, U037654, U056700
Consensus CDS ProjectCCDS28611.1, CCDS50055.1
International Mouse Knockout Project StatusU2af1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 108121 NCBI Gene Model | MGI Sequence Detail 11673 C57BL/6J ±  kb
transcript NM_024187 RefSeq | MGI Sequence Detail 907 C57BL/6 
polypeptide Q9D883 UniProt | EBI | MGI Sequence Detail 239 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(8) UniProt(3)
Polymorphisms SNPs within 2kb(43 from dbSNP Build 137)    SNPs within 2kb including multiple locations(45)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
InterPro IPR009145 U2 auxiliary factor small subunit
InterPro IPR000571 Zinc finger, CCCH-type
Protein Ontology PR:000016944 splicing factor U2AF 35 kDa subunit
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(43)
Other
accession IDs
MGD-MRK-15321, MGI:1914284

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory