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Psmd3 Gene Detail
Summary
  • Symbol
    Psmd3
  • Name
    proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
  • Synonyms
    AntP91a, Psd3, Tstap91a
  • Feature Type
    protein coding gene
  • IDs
    MGI:98858
    NCBI Gene: 22123
  • Gene Overview
    MyGene.info: PSMD3
Location & Maps
more
  • Sequence Map
    Chr11:98682554-98695979 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13426 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 62.39 cM
  • Mapping Data
    9 experiments
  • Sequence Tag
Homology
more
  • Human Ortholog
    PSMD3, proteasome 26S subunit, non-ATPase 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PSMD3, proteasome 26S subunit, non-ATPase 3
    Orthology source: HomoloGene
  • Synonyms
    P58, RPN3, S3, TSTA2
  • Links
    NCBI Gene ID: 5709
    neXtProt AC: NX_O43242

  • Chr Location
    17q21.1; chr17:39980768-39997960 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    16
  • Gene trapped
    11
  • Targeted
    5
  • Genomic Mutations
    1 involving Psmd3
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006404 VEGA Gene Model | MGI Sequence Detail 13426 C57BL/6J ±  kb
transcript OTTMUST00000014585 VEGA | MGI Sequence Detail 2148 Not Applicable  
polypeptide OTTMUSP00000006778 VEGA | MGI Sequence Detail 530 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    80 from dbSNP Build 142
  • PCR
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000013387 26S proteasome non-ATPase regulatory subunit 3
  • InterPro Domains
    IPR013586 26S proteasome regulatory subunit, C-terminal
    IPR000717 Proteasome component (PCI) domain
    IPR011990 Tetratricopeptide-like helical domain
    IPR011991 Winged helix-turn-helix DNA-binding domain
Molecular
Reagents
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  • All nucleic 275
    Genomic 4
    cDNA 268
    Primer pair 3

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-15286, MGD-MRK-34053, MGI:2144092
References
more
  • Summaries
    All 45
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 13
  • Earliest
    J:52726 Uyttenhove C, et al., Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. I. Rejection by syngeneic mice. J Exp Med. 1980 Nov 1;152(5):1175-83
  • Latest
    J:193640 Lo JC, et al., RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet. 2012;8(10):e1002969

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory