About   Help   FAQ
Kdm3a
Gene Detail
Symbol

Name
ID
Kdm3a
lysine (K)-specific demethylase 3A
MGI:98847
Synonyms
1700105C21Rik, C230043E16Rik, Jmjd1, Jmjd1a, mKIAA0742, Tsga
Feature Type
protein coding gene
Genetic Map
Chromosome 6
32.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:71588974-71632905 bp, - strand
From Ensembl annotation of GRCm38

  43932 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10196  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: KDM3A
Gene Tree: Kdm3a

Human
homologs
KDM3A, lysine (K)-specific demethylase 3A
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 55818
neXtProt AC: NX_Q9Y4C1

Human Synonyms: JHDM2A, JHMD2A, JMJD1, JMJD1A, TSGA

Human Chr (Location): 2p11.2; chr2:86440647-86492716 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(84) : Gene trapped(77) Spontaneous(1) Targeted(6)
Genomic Mutations involving Kdm3a (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Male mice homozygous for a hypomorphic allele display infertility, oligoasthenoteratozoospermia, small testis, and impaired spermiogenesis. Mice homozygous for a null allele exhibit abnormal spermatogenesis and obesity associated with hyperlipidemia.
 
Human Diseases Modeled in Mice Using Kdm3a (1)    Mutations Annotated to Human Diseases (1)    Phenotype Images(2)
Interactions
Kdm3a interacts with 245 markers (Mir1b, Mir7-1, Mir10a, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (2)    Tissues (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 2
cDNA source data(275)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase kdm3a    NEW 
Molecular
reagents
All nucleic(277) cDNA(276) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000053470 (Evidence)
Entrez Gene 104263 (Evidence)
UniGene 260479
DFCI TC1572642, TC1590666
DoTS DT.101156341, DT.101280122, DT.110493111, DT.493142, DT.97350439
NIA Mouse Gene Index U027459
EC 1.14.11.-
Consensus CDS Project CCDS20233.1
International Mouse Phenotyping Consortium Status Kdm3a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053470 Ensembl Gene Model | MGI Sequence Detail 43932 C57BL/6J ±  kb
transcript ENSMUST00000065509 Ensembl | MGI Sequence Detail 4814 Not Applicable 
polypeptide ENSMUSP00000065716 Ensembl | MGI Sequence Detail 1323 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(12) UniProt(6)
Polymorphisms
SNPs within 2kb(156 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003347 JmjC domain
Protein Ontology PR:000009211 lysine-specific demethylase 3A
References
(Earliest) J:11619 Hoog C, et al., Analysis of a murine male germ cell-specific transcript that encodes a putative zinc finger protein. Mol Reprod Dev. 1991 Nov;30(3):173-81
(Latest) J:222450 Uribe V, et al., Arid3b is essential for second heart field cell deployment and heart patterning. Development. 2014 Nov;141(21):4168-81
All references(50)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-15272, MGI:1920820, MGI:2444882

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory