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Phf1
Gene Detail
 Symbol
Name
ID
Phf1
PHD finger protein 1
MGI:98647
Synonyms D17Ertd455e, mPcl1, PHF2, Tctex3, Tctex-3
Feature Type protein coding gene
Genetic Map
Chromosome 17
13.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr17:26933127-26937890 bp, + strand
From NCBI annotation of GRCm38

  4764 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7567  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Phf1

Human
homologs
Human Homolog PHF1, PHD finger protein 1
NCBI Gene ID 5252
neXtProt AC  NX_O43189
Human Synonyms  hPHF1, MTF2L2, PCL1, PHF2, TDRD19C
Human Chr (Location)  6p21.3; chr6:33410996-33416453 (+)  GRCh38
Alleles
and
phenotypes
All alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process cellular response to DNA damage stimulus, chromatin modification, ...
Component cytoplasm, cytoskeleton, ...
Function metal ion binding, methylated histone binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (78)    Tissues (74)    Images (5)
Theiler Stages: 2, 3, 4, 5, 15, 17, 21, 23, 28
Assay TypeResults
RNA in situ 63
RT-PCR 15
cDNA source data(59)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(66) Genomic(3) cDNA(59) Primer pair(3) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000024193 (Evidence)
Entrez Gene21652 (Evidence)
UniGene258953
DFCITC1578233, TC1676675
DoTSDT.101366186, DT.532417, DT.97401679, DT.99858585
Consensus CDS ProjectCCDS37518.1
International Mouse Knockout Project StatusPhf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 21652 NCBI Gene Model | MGI Sequence Detail 4764 C57BL/6J ±  kb
transcript NM_009343 RefSeq | MGI Sequence Detail 2429 C57BL/6 
polypeptide Q9Z1B8 UniProt | EBI | MGI Sequence Detail 559 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(7) UniProt(1)
Polymorphisms PCR(1) : SNPs within 2kb(63 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025894 Polycomb-like MTF2 factor 2, C-terminal domain
InterPro IPR002999 Tudor domain
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000012636 PHD finger protein 1
Graphical View of Protein Domain Structure
References (Earliest) J:608 Ha H, et al., Several testis-expressed genes in the mouse t-complex have expression differences between wild-type and t-mutant mice. Dev Genet. 1991;12(4):318-32
(Latest) J:196212 Ballare C, et al., Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity. Nat Struct Mol Biol. 2012 Dec;19(12):1257-65
All references(42)
Other
accession IDs
MGD-MRK-14954, MGD-MRK-14968, MGI:1196283, MGI:2147091

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory