About   Help   FAQ
Phf1 Gene Detail
Summary
  • Symbol
    Phf1
  • Name
    PHD finger protein 1
  • Synonyms
    D17Ertd455e, mPcl1, PHF2, Tctex3, Tctex-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:98647
    NCBI Gene: 21652
  • Gene Overview
    MyGene.info: PHF1
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26933127-26937908 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 13.60 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98647
 protein coding gene Chr17:26933052-26937908 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023410
 protein coding gene Chr17:26157564-26162326 (+)
A/J MGP_AJ_G0023367
 protein coding gene Chr17:25363130-25367892 (+)
AKR/J MGP_AKRJ_G0023333
 protein coding gene Chr17:25496721-25501483 (+)
BALB/cJ MGP_BALBcJ_G0023372
 protein coding gene Chr17:25605151-25609913 (+)
C3H/HeJ MGP_C3HHeJ_G0023133
 protein coding gene Chr17:25872110-25876873 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023815
 protein coding gene Chr17:27263454-27268217 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021289
 protein coding gene Chr17:22774444-22779225 (+)
CAST/EiJ MGP_CASTEiJ_G0022634
 protein coding gene Chr17:25799460-25804226 (+)
CBA/J MGP_CBAJ_G0023107
 protein coding gene Chr17:28215414-28220177 (+)
DBA/2J MGP_DBA2J_G0023239
 protein coding gene Chr17:24925510-24930272 (+)
FVB/NJ MGP_FVBNJ_G0023208
 protein coding gene Chr17:24709606-24714368 (+)
LP/J MGP_LPJ_G0023316
 protein coding gene Chr17:26407498-26412260 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023226
 protein coding gene Chr17:27730462-27735224 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023856
 protein coding gene Chr17:25869983-25874751 (+)
PWK/PhJ MGP_PWKPhJ_G0022384
 protein coding gene Chr17:23724252-23729114 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022202
 protein coding gene Chr17:23906467-23911227 (+)
WSB/EiJ MGP_WSBEiJ_G0022697
 protein coding gene Chr17:25892547-25897313 (+)



Homology
more
  • Human Ortholog
    PHF1, PHD finger protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PHF1, PHD finger protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hPHF1, MTF2L2, PCL1, PHF2, TDRD19C
  • Links
    NCBI Gene ID: 5252
    neXtProt AC: NX_O43189
    UniProt: O43189

  • Chr Location
    6p21.32; chr6:33410751-33416453 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 7567
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PHF1
  • Gene Tree
    Phf1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    698
  • Tissues
    65
  • cDNA Data
    60
  • Literature Summary
    6
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 21652 NCBI Gene Model | MGI Sequence Detail 4782 C57BL/6J ±  kb
transcript NM_009343 RefSeq | MGI Sequence Detail 2447 C57BL/6  
polypeptide Q9Z1B8 UniProt | EBI | MGI Sequence Detail 559 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 66
    Genomic 3
    cDNA 60
    Primer pair 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-14954, MGD-MRK-14968, MGI:1196283, MGI:2147091
References
more
  • Summaries
    All 50
    Developmental Gene Expression 6
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:608 Ha H, et al., Several testis-expressed genes in the mouse t-complex have expression differences between wild-type and t-mutant mice. Dev Genet. 1991;12(4):318-32
  • Latest
    J:281161 Ragazzini R, et al., EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells. Nat Commun. 2019 Aug 26;10(1):3858
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
10/20/2020
MGI 6.16 		The Jackson Laboratory