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Phf1 Gene Detail
Summary
  • Symbol
    Phf1
  • Name
    PHD finger protein 1
  • Synonyms
    D17Ertd455e, mPcl1, PHF2, Tctex3, Tctex-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:98647
    NCBI Gene: 21652
  • Gene Overview
    MyGene.info: PHF1
Location & Maps
more
  • Sequence Map
    Chr17:26933127-26937890 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4764 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 13.60 cM
  • Mapping Data
    6 experiments
Homology
more
  • Human Ortholog
    PHF1, PHD finger protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PHF1, PHD finger protein 1
    Orthology source: HomoloGene
  • Synonyms
    hPHF1, MTF2L2, PCL1, PHF2, TDRD19C
  • Links
    NCBI Gene ID: 5252
    neXtProt AC: NX_O43189

  • Chr Location
    6p21.3; chr6:33410412-33416453 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 7567
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: PHF1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    6
  • Gene trapped
    1
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    2 involving Phf1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024193 Ensembl Gene Model | MGI Sequence Detail 4764 C57BL/6J ±  kb
transcript ENSMUST00000073724 Ensembl | MGI Sequence Detail 2429 Not Applicable  
polypeptide ENSMUSP00000073402 Ensembl | MGI Sequence Detail 559 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    64 from dbSNP Build 142
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 66
    Genomic 3
    cDNA 59
    Primer pair 3
    Other 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-14954, MGD-MRK-14968, MGI:1196283, MGI:2147091
References
more
  • Summaries
    All 42
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:608 Ha H, et al., Several testis-expressed genes in the mouse t-complex have expression differences between wild-type and t-mutant mice. Dev Genet. 1991;12(4):318-32
  • Latest
    J:196212 Ballare C, et al., Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity. Nat Struct Mol Biol. 2012 Dec;19(12):1257-65

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory