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Tcte1 Gene Detail
Summary
  • Symbol
    Tcte1
  • Name
    t-complex-associated testis expressed 1
  • Synonyms
    D17Sil1, Tcte-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:98640
    NCBI Gene: 21645
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr17:45523434-45542679 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19246 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 22.54 cM, cytoband C
  • Mapping Data
    8 experiments
  • Sequence Tag
Homology
more
  • Human Ortholog
    TCTE1, t-complex-associated-testis-expressed 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TCTE1, t-complex-associated-testis-expressed 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    D6S46, DRC5, FAP155
  • Links
    NCBI Gene ID: 202500
    neXtProt AC: NX_Q5JU00
    UniProt: Q5JU00

  • Chr Location
    6p21.1; chr6:44280160-44297805 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8434
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TCTE1
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with Tcte1 mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 21645 NCBI Gene Model | MGI Sequence Detail 19246 C57BL/6J ±  kb
transcript NM_013688 RefSeq | MGI Sequence Detail 3074 C57BL/6  
polypeptide A6H639 UniProt | EBI | MGI Sequence Detail 498 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    117 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    Genomic 1
    cDNA 3
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-14943, MGD-MRK-14946, MGD-MRK-4780
References
more
  • Summaries
    All 29
    Diseases 1
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:8839 Rappold GA, et al., Identification of a testis-specific gene from the mouse t-complex next to a CpG-rich island. EMBO J. 1987 Jul;6(7):1975-80
  • Latest
    J:243766 Castaneda JM, et al., TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa. Proc Natl Acad Sci U S A. 2017 Jul 03;114(27):E5370-E5378

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory