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Trbv13-2 Gene Detail
Summary
  • Symbol
    Trbv13-2
  • Name
    T cell receptor beta, variable 13-2
Location &
Maps
more
  • Sequence Map
    Chr6:41098330-41098766 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 19.20 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    182 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98608
gene segment Chr6:41098330-41098766 (+)
129S1/SvImJ ENSMUSG00200047910
gene segment Chr6:38156165-38156601 (+)
A/J ENSMUSG00195044602
gene segment Chr6:38125854-38126290 (+)
AKR/J ENSMUSG00220009076
gene segment Chr6:37731077-37731513 (+)
BALB/cJ ENSMUSG00180046247
gene segment Chr6:38254271-38254707 (+)
C3H/HeJ ENSMUSG00175050326
gene segment Chr6:38081374-38081810 (+)
C57BL/6NJ ENSMUSG00215047972
gene segment Chr6:38180052-38180488 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0002251
gene segment Chr6:35666184-35666620 (+)
CAST/EiJ ENSTCUG00005037848
gene segment Chr6:37655774-37656210 (+)
CBA/J ENSMUSG00210052458
gene segment Chr6:38133107-38133543 (+)
DBA/2J ENSMUSG00185048674
gene segment Chr6:38235615-38236051 (+)
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000024898
gene segment Chr6:37852877-37853313 (+)
LP/J ENSMUSG00230044293
gene segment Chr6:39159321-39159757 (+)
NOD/ShiLtJ ENSMUSG00190050482
gene segment Chr6:38025095-38025531 (+)
NZO/HlLtJ ENSMUSG00225020954
gene segment Chr6:41141994-41142430 (+)
PWK/PhJ ENSLUMG00010046471
gene segment Chr6:37614675-37615111 (+)
SPRET/EiJ ENSMSPG00010032831
gene segment Chr6:38361558-38361994 (+)
WSB/EiJ ENSIUOG00005034468
gene segment Chr6:38354253-38354689 (+)



Homology
more
  • Human Ortholog
    TRBV10-1, T cell receptor beta variable 10-1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRBV10-1, T cell receptor beta variable 10-1
  • Synonyms
    TCRBV10S1, TCRBV12S2, TCRBV12S2A1T, TRBV101
  • Links
    NCBI Gene ID: 28585
    UniProt: A0A0K0K1A3

  • Chr Location
    7q34; chr7:142399860-142400377 (+)  GRCh38

  • Human Ortholog
    TRBV10-2, T cell receptor beta variable 10-2
  • Synonyms
    TCRBV10S2, TCRBV12S3, TRBV102
  • Links
    NCBI Gene ID: 28584
    UniProt: A0A0K0K1G8

  • Chr Location
    7q34; chr7:142424965-142425465 (+)  GRCh38

  • Human Ortholog
    TRBV10-3, T cell receptor beta variable 10-3
  • Synonyms
    TCRBV10S3, TCRBV12S1A1N2, TRBV103
  • Links
    NCBI Gene ID: 28583
    UniProt: A0A0K0K1G6

  • Chr Location
    7q34; chr7:142544212-142544685 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-in allele exhibit abnormal T cell differentiation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 100124675 NCBI Gene Model | MGI Sequence Detail 437 C57BL/6J ±  kb
transcript L37872 GenBank | ENA | DDBJ | MGI Sequence Detail 685 AKR/J  
polypeptide A0A140T8N6 UniProt | EBI | MGI Sequence Detail 113 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
    IPR050413 T cell receptor beta variable
Molecular
Reagents
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  • All nucleic 18
    Genomic 5
    cDNA 12
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-14900
References
more
  • Summaries
    All 22
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:7995 Barth RK, et al., The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments. Nature. 1985 Aug 8-14;316(6028):517-23
  • Latest
    J:180175 Patel O, et al., Vbeta2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19007-12

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory