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Tcrb
Complex/Cluster/Region Detail
 Symbol
Name
ID
Tcrb
T cell receptor beta chain
MGI:98578
Synonyms TCRbeta, Tib
Feature Type complex/cluster/region
Genetic Map
Chromosome 6
cytoband A-C

Mapping data(68)
Alleles
and
phenotypes
All alleles(19) : Targeted(16) Other(3)
 
Homozygous null mice display thymic hypoplasia, impaired Tcrb V(D)J recombinations, and arrested alphabeta T cell development.
 
Alleles Annotated to Human Diseases(1)   
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cellular response to parathyroid hormone stimulus, positive regulation of calcium-mediated signaling, ...
Component alpha-beta T cell receptor complex, external side of plasma membrane, ...
Function peptide binding, protein binding
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (9)    Tissues (3)   
Theiler Stages: 21, 22, 23
Assay TypeResults
Northern blot 9
cDNA source data(3)
Molecular
reagents
All nucleic(14) Genomic(3) cDNA(6) Primer pair(3) Other(2)
Other database
links
Entrez Gene21577 (Evidence)
DFCITC1757216
DoTSDT.94306829, DT.94336872
Sequences
Representative SequencesLengthStrain/SpeciesFlank
transcript X00439 GenBank | EMBL | DDBJ | MGI Sequence Detail 389 Not Specified 

For the selected sequences
All sequences(6) RefSeq(1)
Polymorphisms All PCR and RFLP(16) : PCR(3) RFLP(13) SNPs within 2kb(0 from dbSNP Build 137)
References (Earliest) J:7353 Hedrick SM, et al., Isolation of cDNA clones encoding T cell-specific membrane-associated proteins. Nature. 1984 Mar 8-14;308(5955):149-53
(Latest) J:205454 Mishra R, et al., Inflammatory cytokine-mediated evasion of virus-induced tumors from NK cell control. J Immunol. 2013 Jul 15;191(2):961-70
All references(550)
Other
accession IDs
MGD-MRK-14870, MGD-MRK-15107

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory