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Tcp11 Gene Detail
Summary
  • Symbol
    Tcp11
  • Name
    t-complex protein 11
  • Synonyms
    D17Ken1, Tcp-11
  • Feature Type
    protein coding gene
  • IDs
    MGI:98544
    NCBI Gene: 21463
  • Gene Overview
    MyGene.info: TCP11
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:28066745-28080639 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 14.62 cM, cytoband A3-B
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    96 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98544
protein coding gene Chr17:28066745-28080726 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023432
protein coding gene Chr17:27414129-27430610 (-)
A/J MGP_AJ_G0023390
protein coding gene Chr17:26546530-26560213 (-)
AKR/J MGP_AKRJ_G0023355
protein coding gene Chr17:26715660-26729435 (-)
BALB/cJ MGP_BALBcJ_G0023395
protein coding gene Chr17:26807777-26821953 (-)
C3H/HeJ MGP_C3HHeJ_G0023156
protein coding gene Chr17:27095939-27115732 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023837
protein coding gene Chr17:28538748-28555592 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021312
protein coding gene Chr17:23917907-23930581 (-)
CAST/EiJ MGP_CASTEiJ_G0022657
protein coding gene Chr17:27074784-27088494 (-)
CBA/J MGP_CBAJ_G0023130
protein coding gene Chr17:29539592-29554680 (-)
DBA/2J MGP_DBA2J_G0023261
protein coding gene Chr17:26095716-26110287 (-)
FVB/NJ MGP_FVBNJ_G0023231
protein coding gene Chr17:25890166-25904786 (-)
LP/J MGP_LPJ_G0023339
protein coding gene Chr17:27677423-27691620 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023249
protein coding gene Chr17:28996807-29019023 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023879
protein coding gene Chr17:27136687-27152134 (-)
PWK/PhJ MGP_PWKPhJ_G0022407
protein coding gene Chr17:24898080-24914141 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022225
protein coding gene Chr17:25147490-25161687 (-)
WSB/EiJ MGP_WSBEiJ_G0022719
protein coding gene Chr17:27130745-27145979 (-)



Homology
more
  • Human Ortholog
    TCP11, t-complex 11
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TCP11, t-complex 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    D6S230E, FPPR
  • Links
    NCBI Gene ID: 6954
    neXtProt AC: NX_Q8WWU5
    UniProt: Q8WWU5

  • Chr Location
    6p21.31; chr6:35118071-35141642 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000062859 Ensembl Gene Model | MGI Sequence Detail 13895 C57BL/6J ±  kb
transcript ENSMUST00000042692 Ensembl | MGI Sequence Detail 1989 Not Applicable  
polypeptide ENSMUSP00000038590 Ensembl | MGI Sequence Detail 567 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 59
    cDNA 59

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-14816, MGD-MRK-14835, MGD-MRK-4493
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:11436 Mazarakis ND, et al., Isolation and characterisation of a testis-expressed developmentally regulated gene from the distal inversion of the mouse t-complex. Development. 1991 Feb;111(2):561-71
  • Latest
    J:236944 Stanger SJ, et al., A novel germ cell protein, SPIF (sperm PKA interacting factor), is essential for the formation of a PKA/TCP11 complex that undergoes conformational and phosphorylation changes upon capacitation. FASEB J. 2016 Aug;30(8):2777-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory