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Ubtf
Gene Detail
Symbol

Name
ID
Ubtf
upstream binding transcription factor, RNA polymerase I
MGI:98512
Synonyms
A930005G04Rik, Tcfubf, UBF, UBF1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
66.29 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:102304560-102319742 bp, - strand
From VEGA annotation of GRCm38

  15183 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7970  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ubtf

Human
homologs
Human Homolog UBTF, upstream binding transcription factor, RNA polymerase I
NCBI Gene ID 7343
neXtProt AC  NX_P17480
Human Synonyms  NOR-90, UBF, UBF1, UBF-1, UBF2
Human Chr (Location)  17q21.31; chr17:44205033-44221626 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(78) : Gene trapped(76) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ubtf interacts with 328 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process chromatin remodeling, chromatin silencing at rDNA, ...
Component fibrillar center, nucleolus, ...
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (107)    Tissues (68)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 99
RT-PCR 8
cDNA source data(149)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(154) Genomic(4) cDNA(149) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000002765 (Evidence)
Ensembl Gene ModelENSMUSG00000020923 (Evidence)
Entrez Gene21429 (Evidence)
UniGene2845
DFCITC1574061, TC1586964, TC1614960, TC1671963
DoTSDT.101254252, DT.101294184, DT.101379061, DT.535057, DT.87072241, DT.94358208, DT.99862593
NIA Mouse Gene IndexU033473
PDB1WGF, 1V63, 1V64
Consensus CDS ProjectCCDS25495.1, CCDS36343.1
International Mouse Knockout Project StatusUbtf
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002765 VEGA Gene Model | MGI Sequence Detail 15183 C57BL/6J ±  kb
transcript OTTMUST00000005525 VEGA | MGI Sequence Detail 4692 Not Applicable 
polypeptide OTTMUSP00000002630 VEGA | MGI Sequence Detail 764 Not Applicable 

For the selected sequences
All sequences(118) RefSeq(20) UniProt(15)
Polymorphisms
SNPs within 2kb(40 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009071 High mobility group (HMG) box domain
Protein Ontology PR:000017017 nucleolar transcription factor 1
References
(Earliest) J:11433 Hisatake K, et al., Cloning and structural analysis of cDNA and the gene for mouse transcription factor UBF. Nucleic Acids Res. 1991 Sep 11;19(17):4631-7
(Latest) J:198536 Nonnekens J, et al., Mutations in TFIIH causing trichothiodystrophy are responsible for defects in ribosomal RNA production and processing. Hum Mol Genet. 2013 Jul 15;22(14):2881-93
All references(56)
Other
accession IDs
MGD-MRK-14765, MGI:1925846

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory