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Tfcp2
Gene Detail
Symbol

Name
ID
Tfcp2
transcription factor CP2
MGI:98509
Synonyms
CP2, CP-2, D230015P20Rik, LBP1, LBP-1c, LBP-1d, LSF, Tcfcp2, UBP-1
Feature Type
protein coding gene
Genetic Map
Chromosome 15
56.33 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:100502799-100552008 bp, - strand
From Ensembl annotation of GRCm38

  49210 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4134  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Tfcp2

Human
homologs
Human Homolog TFCP2, transcription factor CP2
NCBI Gene ID 7024
neXtProt AC  NX_Q12800
Human Synonyms  LBP1C, LSF, LSF1D, SEF, TFCP2C
Human Chr (Location)  12q13; chr12:51093756-51173143 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(6) Radiation induced(1) Targeted(3)
Genomic Mutations involving Tfcp2 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele are viable, fertile and overtly normal with no apparent alterations in overall behavior, hematopoiesis, globin chain synthesis, or immunological function.
 
Interactions
Tfcp2 interacts with 248 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (77)    Tissues (56)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 69
RT-PCR 8
cDNA source data(30)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(37) Genomic(6) cDNA(30) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000009733 (Evidence)
Entrez Gene21422 (Evidence)
UniGene219040
DFCITC1580744, TC1590949, TC1595742, TC1613019
DoTSDT.55206245, DT.91446463, DT.97366277, DT.99853298
NIA Mouse Gene IndexU036667
Consensus CDS ProjectCCDS27840.1
International Mouse Knockout Project StatusTfcp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000009733 Ensembl Gene Model | MGI Sequence Detail 49210 C57BL/6J ±  kb
transcript ENSMUST00000009877 Ensembl | MGI Sequence Detail 3250 Not Applicable 
polypeptide ENSMUSP00000009877 Ensembl | MGI Sequence Detail 502 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(18) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(188 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007604 CP2 transcription factor
InterPro IPR013761 Sterile alpha motif/pointed domain
Protein Ontology PR:000029786 alpha-globin transcription factor CP2
References
(Earliest) J:2323 Lim LC, et al., Molecular cloning of the alpha-globin transcription factor CP2. Mol Cell Biol. 1992 Feb;12(2):828-35
(Latest) J:171731 Porta-de-la-Riva M, et al., TFCP2c/LSF/LBP-1c is required for Snail1-induced fibronectin gene expression. Biochem J. 2011 May 1;435(3):563-8
All references(41)
Other
accession IDs
MGD-MRK-14761, MGI:2442498

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory