About   Help   FAQ
Tfcp2
Gene Detail
Symbol

Name
ID
Tfcp2
transcription factor CP2
MGI:98509
Synonyms
CP2, CP-2, D230015P20Rik, LBP1, LBP-1c, LBP-1d, LSF, Tcfcp2, UBP-1
Feature Type
protein coding gene
Genetic Map
Chromosome 15
56.33 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:100502799-100552008 bp, - strand
From Ensembl annotation of GRCm38

  49210 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4134  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TFCP2
Gene Tree: Tfcp2

Human
homologs
TFCP2, transcription factor CP2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 7024
neXtProt AC: NX_Q12800

Human Synonyms: LBP1C, LSF, LSF1D, SEF, TFCP2C

Human Chr (Location): 12q13; chr12:51093756-51173143 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(6) Radiation induced(1) Targeted(3)
Genomic Mutations involving Tfcp2 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele are viable, fertile and overtly normal with no apparent alterations in overall behavior, hematopoiesis, globin chain synthesis, or immunological function.
 
Phenotype Images(2)
Interactions
Tfcp2 interacts with 248 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (77)    Tissues (56)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 69
RT-PCR 8
cDNA source data(30)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase tfcp2    NEW 
Molecular
reagents
All nucleic(37) Genomic(6) cDNA(30) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000009733 (Evidence)
Entrez Gene 21422 (Evidence)
UniGene 219040
DFCI TC1580744, TC1590949, TC1595742, TC1613019
DoTS DT.55206245, DT.91446463, DT.97366277, DT.99853298
NIA Mouse Gene Index U036667
Consensus CDS Project CCDS27840.1
International Mouse Phenotyping Consortium Status Tfcp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000009733 Ensembl Gene Model | MGI Sequence Detail 49210 C57BL/6J ±  kb
transcript ENSMUST00000009877 Ensembl | MGI Sequence Detail 3250 Not Applicable 
polypeptide ENSMUSP00000009877 Ensembl | MGI Sequence Detail 502 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(10) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(188 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007604 CP2 transcription factor
InterPro IPR013761 Sterile alpha motif/pointed domain
Protein Ontology PR:000029786 alpha-globin transcription factor CP2
References
(Earliest) J:2323 Lim LC, et al., Molecular cloning of the alpha-globin transcription factor CP2. Mol Cell Biol. 1992 Feb;12(2):828-35
(Latest) J:171731 Porta-de-la-Riva M, et al., TFCP2c/LSF/LBP-1c is required for Snail1-induced fibronectin gene expression. Biochem J. 2011 May 1;435(3):563-8
All references(41)
Other
accession IDs
MGD-MRK-14761, MGI:2442498

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/25/2015
MGI 6.0
The Jackson Laboratory