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Tat
Gene Detail
Symbol

Name
ID
Tat
tyrosine aminotransferase
MGI:98487
Synonyms
MGC:37772, MGC:37789, MGC:37790, MGC:37819, MGC:37828, MGC:37842
Feature Type
protein coding gene
Genetic Map
Chromosome 8
57.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(20)
Sequence Map
Chr8:109990437-109999803 bp, + strand
From VEGA annotation of GRCm38

  9367 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37293  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: tyrosine transaminase
Gene Tree: Tat

Human
homologs
Human Homolog TAT, tyrosine aminotransferase
NCBI Gene ID 6898
neXtProt AC  NX_P17735
Human Chr (Location)  16q22.1; chr16:71566851-71577095 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human TAT
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tat interacts with 100 markers (Mir10a, Mir10b, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process 2-oxoglutarate metabolic process, aromatic amino acid family catabolic process, ...
Component mitochondrion
Function amino acid binding, catalytic activity, ...
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (130)    Tissues (100)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
Northern blot 30
RT-PCR 6
cDNA source data(117)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(132) Genomic(9) cDNA(119) Primer pair(2) Other(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000026257 (Evidence)
Ensembl Gene ModelENSMUSG00000001670 (Evidence)
Entrez Gene234724 (Evidence)
UniGene28110
DFCITC1576826
DoTSDT.494658
NIA Mouse Gene IndexU009814
EC2.6.1.5
PDB3PDX
Consensus CDS ProjectCCDS22658.1
International Mouse Knockout Project StatusTat
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026257 VEGA Gene Model | MGI Sequence Detail 9367 C57BL/6J ±  kb
transcript OTTMUST00000064935 VEGA | MGI Sequence Detail 2375 Not Applicable 
polypeptide OTTMUSP00000032296 VEGA | MGI Sequence Detail 454 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(5)
Polymorphisms
All PCR and RFLP(6) : PCR(1) RFLP(5) SNPs within 2kb(14 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004839 Aminotransferase, class I/classII
InterPro IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site
InterPro IPR015424 Pyridoxal phosphate-dependent transferase
InterPro IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1
InterPro IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2
InterPro IPR005957 Tyrosine aminotransferase
InterPro IPR011715 Tyrosine aminotransferase ubiquitination region
InterPro IPR005958 Tyrosine/nicotianamine aminotransferase
InterPro IPR021178 Tyrosine transaminase
Protein Ontology PR:000016089 tyrosine aminotransferase
References
(Earliest) J:25840 Blake RL, Regulation of liver tyrosine aminotransferase activity in inbred strains and mutant mice, I. Strain variance in fasting enzyme levels. Int J Biochem. 1970;1:361-70
(Latest) J:199204 Kiyohashi K, et al., Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13
All references(68)
Other
accession IDs
MGD-MRK-14719

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory