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Tacr2
Gene Detail
Symbol

Name
ID
Tacr2
tachykinin receptor 2
MGI:98477
Synonyms
Tac2r
Feature Type
protein coding gene
Genetic Map
Chromosome 10
32.37 cM, cytoband B4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:62252438-62265990 bp, + strand
From NCBI annotation of GRCm38

  13553 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55548  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: tachykinin receptor
Gene Tree: Tacr2

Human
homologs
Human Homolog TACR2, tachykinin receptor 2
NCBI Gene ID 6865
neXtProt AC  NX_P21452
Human Synonyms  NK2R, NKNAR, SKR, TAC2R
Human Chr (Location)  10q22.1; chr10:69404202-69416918 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Interactions
Tacr2 interacts with 153 markers (Mir17, Mir19a, Mir19b-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (27)    Tissues (18)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 24
RT-PCR 3
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) Genomic(3) cDNA(7) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000020081 (Evidence)
Entrez Gene21337 (Evidence)
UniGene8054
DFCITC1590287
DoTSDT.91328073
NIA Mouse Gene IndexU011577
Consensus CDS ProjectCCDS35919.1
International Mouse Knockout Project StatusTacr2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 21337 NCBI Gene Model | MGI Sequence Detail 13553 C57BL/6J ±  kb
transcript NM_009314 RefSeq | MGI Sequence Detail 2258 C57BL/6 
polypeptide P30549 UniProt | EBI | MGI Sequence Detail 384 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(5)
Polymorphisms
SNPs within 2kb(89 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR000913 Neurokinin NK2 receptor
InterPro IPR001681 Neurokinin receptor
Protein Ontology PR:000001246 substance-K receptor
Graphical View of Protein Domain Structure
References
(Earliest) J:2342 Sundelin JB, et al., Molecular cloning of the murine substance K and substance P receptor genes. Eur J Biochem. 1992 Feb 1;203(3):625-31
(Latest) J:188444 Kitamura H, et al., Neuropeptide signaling activates dendritic cell-mediated type 1 immune responses through neurokinin-2 receptor. J Immunol. 2012 May 1;188(9):4200-8
All references(32)
Other
accession IDs
MGD-MRK-14704

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory