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Surf6 Gene Detail
Summary
  • Symbol
    Surf6
  • Name
    surfeit gene 6
  • Synonyms
    D2Wsu129e, Surf-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:98447
    NCBI Gene: 20935
  • Member of
    Surf cluster
  • Gene Overview
    MyGene.info: SURF6
Location & Maps
more
  • Sequence Map
    Chr2:26888628-26902879 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14252 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 19.08 cM
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    SURF6, surfeit 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SURF6, surfeit 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RRP14
  • Links
    NCBI Gene ID: 6838
    neXtProt AC: NX_O75683

  • Chr Location
    9q34.2; chr9:133330707-133336210 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 133981
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: SURF6
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    7
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011581 VEGA Gene Model | MGI Sequence Detail 14252 C57BL/6J ±  kb
transcript OTTMUST00000027066 VEGA | MGI Sequence Detail 2971 Not Applicable  
polypeptide OTTMUSP00000012334 VEGA | MGI Sequence Detail 355 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    56 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000015843 surfeit locus protein 6
  • InterPro Domains
    IPR029190 Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain
    IPR007019 Surfeit locus 6
Molecular
Reagents
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  • All nucleic 16
    Genomic 2
    cDNA 10
    Primer pair 3
    Other 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-14650, MGD-MRK-14655, MGD-MRK-35818, MGI:107352
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:10274 Huxley C, et al., The mouse surfeit locus contains a cluster of six genes associated with four CpG-rich islands in 32 kilobases of genomic DNA. Mol Cell Biol. 1990 Feb;10(2):605-14
  • Latest
    J:114487 Romanova LG, et al., Implication of Nucleolar Protein SURF6 in Ribosome Biogenesis and Preimplantation Mouse Development. Biol Reprod. 2006 Nov;75(5):690-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory